Propranolol for migraine prophylaxis

Linde, Klaus; Rossnagel, Karin

doi:10.1002/14651858.cd003225.pub2

Cited by 144 publications

(100 citation statements)

References 75 publications

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“…Medication withdrawal will often bring initial misery, but asthmatic patient or for athletes. [24] Topiramate is a good choice eventual benefit is achieved after medication washout. If the for an obese person, [25,26] while cyproheptadine [27] or a tricyclic effects of medication withdrawal are anticipated to be severe, antidepressant [28] would help a patient to gain weight.…”

Section: Preventionmentioning

confidence: 99%

Management of Chronic Daily Headache in??Children and Adolescents

Mack

Gladstein

2008

Pediatric Drugs

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Chronic daily headache (CDH) occurs in 1-2% of children and adolescents. It can evolve from either episodic tension-type headache or episodic migraine, or can appear with no previous headache history. As with other primary headache disorders, treatment is based on the level of disability. There are children and adolescents who cope well, but there are others who are markedly disabled by their chronic headaches. As in adults, children and adolescents with CDH are at risk for medication overuse. CDH is a diagnosis of exclusion, based on a thorough history, normal physical examination, and negative neuroimaging findings. Along with the chronic headaches, children with this condition may have co-morbid sleep problems, autonomic dysfunction, anxiety, and/or depression. Principles of treatment include identifying migrainous components, stopping medication overuse, stressing normalcy, using rational pharmacotherapy, and addressing co-morbid conditions. Successful outcomes often involve identifying an appropriate headache preventative, reintegration into school, and family participation in resetting realistic expectations.

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Section: Preventionmentioning

confidence: 99%

Management of Chronic Daily Headache in??Children and Adolescents

Mack

Gladstein

2008

Pediatric Drugs

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“…Birçok kontrollü çalışmada nonselektif β bloker propranolol ve selektif β-bloker metoprolol'un migren profilaksisinde etkinliği gösterilmiştir (12,13,14,15). Atenolol, nebivolol, bisoprolol, nadolol ve timolol da etkin bulunurken intrensek sempatomimetik aktivite gösteren asebutolol, alprenolol, oksprenolol ve pindolol ise migren profilaktik tedavisinde etkinliğe sahip değildirler (16,17,18,19).…”

Section: Profilaktik Tedavi Etki Mekanizmalarıunclassified

Migrende Profilaktik Tedavi

Gürsoy¹,

Ertaş²

2013

npa

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Migraine is a common chronic neurological disease characterized by episodic attacks of headache and associated symptoms. The pharmacological treatment of migraine may be acute or prophylactic, and patients with frequent, severe headaches often require both approaches. Prophylactic treatment is used to reduce the frequency, duration, or severity of attacks, to enhance the benefits of acute treatments, and to improve patient's ability to function normally. Prophylactic treatment may also prevent progression from episodic migraine to chronic migraine and may result in reductions in health-care cost. The currently available pharmacological options for migraine prophylaxis include a wide array of medications. The major medication groups for prophylactic treatment include β-blockers, anticonvulsant, drugs such as topiramate and valproate, antidepressant drugs, such as amitriptyline and selective serotonin and selective serotonin-norepinephrine reuptake inhibitors (SNRIs), calcium channel antagonists and neurotoxins. The agent for prophylactic treatment should be chosen based on the efficacy and side-effect profile of the drug, and the patient's coexistent and comorbid conditions.

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“…A Cochrane review of available studies in 2004 concluded that propranolol is effective in preventing migraines in the short term, with insufficient data to make a conclusion regarding long term treatment. 9 Sustained release options offer the benefits of once daily dosing and improved compliance. β blockers are a good choice of preventive drug for patients with coexistent hypertension, but they should not be used for patients with asthma and must be used with caution in patients with depression.…”

Section: β Blockersmentioning

confidence: 99%