Proposed Revision of the Icrp Model for Inhaled Mercury Vapor

Rw, Leggett; Nb, Munro; Kf, Eckerman

doi:10.1097/00004032-200110000-00010

Cited by 7 publications

(13 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The ICRP's assumptions are not consistent with current information on the gross distribution or residence time of mercury vapor in the respiratory tract (Leggett et al, 2001). It appears that inhaled mercury vapor deposits largely in the AI region, that most of the deposited mercury is nearly instantaneously absorbed to blood, and that the remainder may have multiple components of retention in the lungs.…”

Section: Changes In the Treatment Of Gases And Vaporsmentioning

confidence: 97%

“…Comparison of dose coefficients for inhaled mercury vapor given in ICRP Publication 68 with values derived from a revised model (Leggett et al, 2001) ........…”

Section: 8mentioning

confidence: 99%

“…It appears that inhaled mercury vapor deposits largely in the AI region, that most of the deposited mercury is nearly instantaneously absorbed to blood, and that the remainder may have multiple components of retention in the lungs. An alternate model of the distribution and retention of inhaled mercury vapor in the respiratory tract has been proposed (Leggett et al, 2001). The proposed model differs from that of ICRP Publication 68 in several ways.…”

Section: Changes In the Treatment Of Gases And Vaporsmentioning

confidence: 99%

See 2 more Smart Citations

Dosimetric Significance of the ICRP's Updated Guidance and Models, 1989-2003, and Implications for U.S. Federal Guidance

Leggett¹

2003

View full text Add to dashboard Cite

Over the past two decades the U.S. Environmental Protection Agency (EPA) has issued a series of Federal guidance documents for the purpose of providing the Federal and State agencies with technical information to assist their implementation of radiation protection programs. Currently recommended dose conversion factors, annual limits on intake, and derived air concentrations for intake of radionuclides are tabulated in Federal Guidance Report No. 11 (FGR 11), published in 1988. The tabulations in FGR 11 were based on dosimetric quantities and biokinetic and dosimetric models of the International Commission on Radiological Protection (ICRP) developed for application to occupational exposures. Since the publication of FGR 11 the ICRP has revised some of its dosimetric quantities and its models for workers and has also developed age-specific models and dose conversion factors for intake of radionuclides by members of the public. This report examines the extent of the changes in the inhalation and ingestion dose coefficients of FGR 11 implied by the updated recommendations of the ICRP, both for workers and members of the public.

show abstract

Section: Changes In the Treatment Of Gases And Vaporsmentioning

confidence: 97%

“…Comparison of dose coefficients for inhaled mercury vapor given in ICRP Publication 68 with values derived from a revised model (Leggett et al, 2001) ........…”

Section: 8mentioning

confidence: 99%

Section: Changes In the Treatment Of Gases And Vaporsmentioning

confidence: 99%

See 1 more Smart Citation

Dosimetric Significance of the ICRP's Updated Guidance and Models, 1989-2003, and Implications for U.S. Federal Guidance

Leggett¹

2003

View full text Add to dashboard Cite

show abstract

“…The model incorporated the International Commission on Radiological Protection (ICRP) lung model [28]. The Hg vapor inhalation model was implemented using the Virtual Human PSE Java client interface to compute human Hg vapor uptake, retention, and excretion [29]. Since the model for Hg vapor is linear, it was implemented in Java by providing the transfer matrix using the PhysioML file.…”

Section: Exposure To Environmental and Occupational Contaminantsmentioning

confidence: 99%

Virtual Human Problem-Solving Environments

Ward

Pouchard²,

Munro

et al. 2008

Digital Human Modeling

View full text Add to dashboard Cite

Abstract. Interest in complex integrated digital or virtual human modeling has seen a significant increase over the last decade. Coincident with that increased interest, Oak Ridge National Laboratory (ORNL) initiated the development of a human simulation tool, the Virtual Human. The Virtual Human includes a problem-solving environment (PSE) for implementing the integration of physiological models in different programming languages and connecting physiological function to anatomy. The Virtual Human PSE (VHPSE) provides the computational framework with which to develop the concept of a "Virtual Human." Supporting the framework is a data definition for modeling parameters, PhysioML, a Virtual Human Database (VHDB), and a Web-based graphical user interface (GUI) developed using Java. Following description of the VHPSE, we discuss four example implementations of models within the framework.Further expansion of a human modeling environment was carried out in the Defense Advanced Research Projects Agency Virtual Soldier Project. SCIRun served as the Virtual Soldier problem solving environment (VSPSE). We review and compare specific developments in these projects that have significant potential for the future of Virtual Human modeling and simulation. We conclude with an evaluation of areas of future work that will provide important extensions to the VHPSE and VSPSE and make possible a fully-integrated environment for human anatomical and physiological modeling: the Virtual Human.

show abstract

“…When atmospheric Hg is inhaled, approximately 80% of it is deposited in the respiratory tract. Then, most (70%) of the deposited Hg is absorbed into the blood almost instantly, whereas the remainder is further absorbed over the course of several hours or days 4 …”

Section: Introductionmentioning

confidence: 99%

DiMIZA: A dispersion modeling based impact zone assessment of mercury (Hg) emissions from coal‐fired power plants and risk evaluation for inhalation exposure

Karaca

Kumisbek

Inglezakis

et al. 2020

Engineering Reports

View full text Add to dashboard Cite

Coal‐fired combined heat and power plants (CHPPs) serving large districts are among the major sources of mercury (Hg) emissions globally, including Central Asia. Most CHPPs reside on the outskirts of urban areas, thus creating risk zones. The impact of atmospheric Hg levels on health is complex to establish due to the site‐specific nature of the relationship between CHPP emissions and hotspots (i.e., localized areas where Hg concentrations greatly exceed its background value). However, a methodological identification of “emission impact zones” for atmospheric Hg emissions from CHPPs with potential adverse public health outcomes has not yet been fully studied. The present work suggests an easy‐to‐use and cost‐free impact zone identification method based on HYSPLIT dispersion modeling for atmospheric Hg emissions from CHPPs. The dispersion modeling based impact zone assessment, DiMIZA, merges short‐term dispersion runs (e.g., hourly) into long‐term emission impacts (e.g., yearly), which allows to identify the source impact zones. To perform a case study using the suggested method, a CHPP plant in Nur‐Sultan (capital of Kazakhstan) was selected. First, traditional ad‐hoc measurements were performed to identify the level of dispersions at ground level in different atmospheric stability characteristics. Then, HYSPLIT dispersion model was run for the same days and times of those particular periods when the field measurements were performed. The model results were evaluated via a comparison with the ground measurements and assessed for their atmospheric stability and diel conditions. Due to different emission loads in heating and non‐heating periods, two separate pairs of impact zone maps were generated, and public Hg exposure health risks (acute and chronic) were assessed.

show abstract

Proposed Revision of the Icrp Model for Inhaled Mercury Vapor

Cited by 7 publications

References 16 publications

Dosimetric Significance of the ICRP's Updated Guidance and Models, 1989-2003, and Implications for U.S. Federal Guidance

Dosimetric Significance of the ICRP's Updated Guidance and Models, 1989-2003, and Implications for U.S. Federal Guidance

Virtual Human Problem-Solving Environments

DiMIZA: A dispersion modeling based impact zone assessment of mercury (Hg) emissions from coal‐fired power plants and risk evaluation for inhalation exposure

Contact Info

Product

Resources

About