Proposal of New Emulsion Systems Containing Hydroxypropylmethylcellulose as a Viscosity Modifier and Diacylglycerols from Mutton Tallow and Hemp Seed Oil

Abstract

The purpose of this study was to analyze the stability of new emulsions prepared on the basis of modified fats with varying amounts of hydroxypropylmethylcellulose. Selected techniques for evaluating the stability of emulsion systems, such as Turbiscan analysis, and the evaluation of microstructure, texture, particle size and viscosity were used. The evaluation of the above-mentioned studied parameters allowed us to indicate differentiated stability and their properties. The most desired results in terms of stability evaluation were determined for the emulsion prepared on the basis of modified mutton tallow with hemp seed oil in a ratio 3:1 (by weight) containing 0.6% (by weight) of hydroxypropylmethylcellulose. In addition, as the hemp seed oil content in the interesterified fat phase increased, a decrease in the stability of the emulsion systems was noted. Mentioned emulsions were characterized with the lowest value of TSI. Moreover, for those emulsions, the smallest increment in the droplet diameter values of systems after 31 days was recorded. The prepared model formulation can serve as a starting material for new emulsion chemical, cosmetic or food systems.

Preparation of Asymmetric Al2O3-SiO2 Janus Nanoparticles in Aqueous Phase and Its Interfacial Property

“…However, A 25KH550 -COOH@S 25HMDS-KH230 could effectively stabilize emulsions of different oil and water mixtures, forming a stable emulsion layer with a thickness of 3.2cm. The effect of amphiphilic asymmetric Al 2 O 3 -SiO 2 Janus nanoparticles on the stability of four oil–water emulsions was then further evaluated by Turbiscan based on the backscattering technology [ 40 , 41 ]. Given that one end of Al 2 O 3 -SiO 2 Janus nanoparticles exhibits anion properties, a common anionic surfactant, namely sodium dodecyl sulfate, was selected for comparison with A 25KH550 -COOH@S 25HMDS-KH230 and A 25KH550 -COOH@S 25HMDS .…”

Curcumin-Based Ionic Liquid Hydrogel for Topical Transdermal Delivery of Curcumin To Improve Its Therapeutic Effect on the Psoriasis Mouse Model

“…However, the use of SA alone will have some limitations, such as poor mechanical properties, poor stability in vivo, vulnerability to an acid–base environment, inability to load hydrophobic drugs, and unstable controlled release of hydrophilic drugs . Hydroxypropyl methyl cellulose (HPMC) is widely used as an auxiliary material for controlled release systems due to its good biocompatibility, stability to temperature and acid–base changes, high mechanical strength, and viscosity. − However, transdermal drug delivery preparations require hydrogel materials with good biocompatibility, high stability, large drug loading, and excellent continuous adhesion. The three-dimensional reticular hydrogel with a simple structure has limited functions and cannot meet actual clinical needs.…”