2002
DOI: 10.1016/s0378-1135(01)00428-x
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Proposal of a new serovar of Actinobacillus pleuropneumoniae: serovar 15

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Cited by 191 publications
(152 citation statements)
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“…Serotyping against serovars 1 to 12 and 15 was conducted by agar gel diffusion testing as previously described [1,11]. Of the 101 strains, serovar 2 (66 isolates from 24 prefectures) was the most common, followed by serovar 5 (14 isolates from 8 prefectures), serovar 1 (8 isolates from 6 prefectures) and serovar 15 (2 isolates from 2 prefectures).…”
mentioning
confidence: 99%
“…Serotyping against serovars 1 to 12 and 15 was conducted by agar gel diffusion testing as previously described [1,11]. Of the 101 strains, serovar 2 (66 isolates from 24 prefectures) was the most common, followed by serovar 5 (14 isolates from 8 prefectures), serovar 1 (8 isolates from 6 prefectures) and serovar 15 (2 isolates from 2 prefectures).…”
mentioning
confidence: 99%
“…A sorotipificação de App pode ser realizada diretamente, pelas técnicas de aglutinação em látex, hemaglutinação indireta e testes de difusão em gel, ou de forma empírica através da análise do perfil de toxinas Apx presentes nos isolados (FREY, 1995;BLACKALL et al, 2002). Entretanto, muitos problemas são observados, como reações cruzadas, presença de Ciência Rural, v. 34, n.4, jul-ago, 2004. amostras auto-aglutinantes e, principalmente, ocorrência de amostras não-sorotipifícáveis (INZANA & MATHISON, 1987).…”
Section: Diagnóstico E Sorotipificação De Appunclassified
“…Destes, doze foram classificados no biótipo 1, enquanto que outros dois no biótipo 2 (DOM et al, 1994). Recentemente, o sorotipo 15 de App foi proposto para isolados australianos, que se distinguem consideravelmente dos demais (BLACKALL et al, 2002). Observações a campo indicaram que os sorotipos 1, 5, 9, 10 e 11 são os mais virulentos, estando geralmente envolvidos em surtos severos, com extensas lesões pulmonares e elevada mortalidade (HAESEBROUCK et al, 1997).…”
Section: Introdução a Pleuropneumonia Suína E A Bactéria Actinobacillunclassified
“…However, the many serotypes of APP have made effective vaccination difficult. Various studies have been carried out to identify vaccine candidates for efficient cross-protection, such as killed bacterin vaccines and subunit vaccines (Blackall et al 2002;Haesebrouck et al 2004;Zhou et al 2013). These vaccine candidates do not prevent colonization and are not widely cross-protective (Tumamao et al 2004).…”
Section: Introductionmentioning
confidence: 99%
“…The 15 serotypes of APP produce four different Apx toxins including ApxI, ApxII, ApxIII and ApxIV (Zhou et al 2013). ApxIA and ApxIIA toxins contribute to hemolytic and cytotoxic functions (Frey & Kuhnert 2002). ApxIIIA has no hemolytic activity but shows strong cytotoxic activity towards alveolar macrophages and neutrophils (Cruijsen et al 1992;Rycroft et al 1991).…”
Section: Introductionmentioning
confidence: 99%