Propolis inspired sunscreens for efficient UV-protection and skin barrier maintenance

In Situ Fabrication of Robust Polyphenolic Hydrogels for Skin Protection and Repair

“…Consistent with the collagen staining data, more alpha-SMA positive cells were detected in the hydrogel group (Figure e,h). Generally, fibroblasts would polarize into myofibroblasts with alpha-SMA expression at the wound site, which would be responsible for ECM protein-like collagen production and remodeling . Hence, it is highly possible that hydrogels did play a role in restraining wound inflammation via ROS scavenging, which then allowed more fibroblast proliferation to form granulation tissue and collagen deposition.…”

Robust and multifunctional natural polyphenolic composites for water remediation

“…The high reactivity of nature-inspired phenolic chemistry has remarkably nourished the development of materials science and also facilitated the assembly as well as stabilization of phenolic NPs with defined sizes and monodisperse characteristics. 15,119 For example, our group has successfully prepared several types of natural phenolic NPs derived from green tea, 120,121 grape seed, 122 propolis, 123 gallic acid (GA), 124 and explored their effects on UV protection and radicals scavenging capacity. In other studies, some functionalized NPs derived from tea polyphenols and fruit polyphenols were synthesized and showed effective removal capacity of heavy metal ions, antibiotics, and bacteria in wastewater.…”

An injectable all-small-molecule dynamic metallogel for suppressing sepsis

“…1,12,13 Although a few cases have been successfully reported, the use of natural polyphenols to construct hydrogels has met with several profound challenges, which was related to the inherent disadvantages of natural polyphenols, such as being easily oxidized and long-term instability. [14][15][16][17][18][19] Therefore, it is crucial to search and screen more kinds of suitable naturally occurring and commercial small molecular synthons to expand the scope of all-smallmolecule dynamic hydrogels with fascinating properties.…”