Abstract:Alzheimer s disease AD is one of the most common causes of dementia, characterized by the accumulation of amyloid-A peptide deposits in the brain. Within an aging society, elderly patients with preoperative dementia, or those who are affected by postoperative cognitive impairment, are a major health problem. Although inhalation anesthetics induce accumulation of A protein and progression of AD, propofol, a short-acting intravenous anesthetic, has gained increasing attention for its neuroprotective effects foll… Show more
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