“…Prophylaxis of the various sheep diseases has been tried with both antitoxin and toxoid vaccinations (27,68,69,212). In experiments of this nature, it is important that the cross-protective powers of the antisera produced for the several species be known, because investigation of the distribution of the diseases has shown that the organisms may occur widely and at random, -B. paludis has been reported in France, Greece and Turkey; B. ovitoxicus in Scotland, North Wales, Palestine, United States, etc.…”