1970
DOI: 10.1159/000468064
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Prophylaktische Lithiumtherapie bei manisch-depressivem Krankheitsgeschehen und bei Legierungspsychosen

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Cited by 18 publications
(3 citation statements)
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“…All 10 studies used lithium carbonate for prophylaxis. Some of the earlier studies report a better response in bipolar patients (67-72 percent, n = 365) than in schizoaffective manic patients (40-53 percent, n -97) (Angst et al 1970;Hofmann et al 1970;Klett 1973, 1974). The finding of Angst et al (1970) that lithium significantly reduced the frequency of episodes in schizoaffective patients and the report of Klett (1973, 1974) that the relapse rate of schizoaffective patients increased to 60 percent after the discontinuation of lithium strongly indicate that lithium was exerting a prophylactic action, even in the absence of a placebo control.…”
Section: Prophylaxis Of Schizoaffective Disordersmentioning
confidence: 95%
“…All 10 studies used lithium carbonate for prophylaxis. Some of the earlier studies report a better response in bipolar patients (67-72 percent, n = 365) than in schizoaffective manic patients (40-53 percent, n -97) (Angst et al 1970;Hofmann et al 1970;Klett 1973, 1974). The finding of Angst et al (1970) that lithium significantly reduced the frequency of episodes in schizoaffective patients and the report of Klett (1973, 1974) that the relapse rate of schizoaffective patients increased to 60 percent after the discontinuation of lithium strongly indicate that lithium was exerting a prophylactic action, even in the absence of a placebo control.…”
Section: Prophylaxis Of Schizoaffective Disordersmentioning
confidence: 95%
“…It is of note that the mirror-image studies can be biased toward responders because patients have to be stable. In a few papers, it was reported that the schizoaffective patients were affected more by lithium than were purely affective patients [6,14], but most authors have observed the opposite [5,8,35]. It is possible that the response might be better in patients with typical affective syndromes and worse in schizophrenia-like patients [38,46].…”
Section: Clozapinementioning
confidence: 99%
“…In den folgenden Jahren konnte diese sedierende Wirkung immer wieder bestätigt werden (24,59). In den letzten Jahren gewann das Lithium eine neue und besondere Bedeutung dadurch, daß neben dem bereits bekannten Effekt bei akuten Manien, in mehreren Arbeiten (4,6,7,9,10,11,12,13,14,15,21,22,27,29,30,33,34,36,37,42,44,47,50,51,52,55,56,62,63,64) über, eine prophylaktische Wirkung bei manisch-depressiven Erkrankungen berichtet wurde. Diese Untersuchungen waren für eine Reihe von Psychiatrischen Kliniken Anlaß, sich dieser neuen Behandlungsmethode zuzuwenden und eigene Erfahrungen zu sammeln.…”
Section: Zusammenfassungunclassified