Prophylactic Magnesium Sulfate for Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Meta-analysis

Reddy, Deven; Fallah, Aria; Petropoulos, Jo‐Anne; Farrokhyar, Forough; Macdonald, R. Loch; Jichici, Draga

doi:10.1007/s12028-014-9964-0

Cited by 33 publications

(19 citation statements)

References 11 publications

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“…Funnel plots were used to analyze whether publication bias exists in the included studies. Metaanalysis was conducted using Review Manager 5.1 software (Cochrane collaboration, Copenhagen, Denmark) 17 . The Quality in Prognostic Studies (QUIPS) tool was used for assessment of study reliability 18 .…”

Section: Data Extraction and Synthesismentioning

confidence: 99%

Direct Anterior Approach Versus Posterolateral Approach in Total Hip Arthroplasty: A Systematic Review and Meta‐analysis of Randomized Controlled Studies

Yang

Huang

et al. 2020

Orthopaedic Surgery

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Objective To compare the early rehabilitation effects of total hip arthroplasty (THA) with the direct anterior approach (DAA) versus the posterior approach (PA). Methods We searched PubMed, Embase, Web of Science, the Cochrane Library, and Google databases from inception to June 2019 to select studies that compared the DAA and PA for THA. Only randomized controlled trials (RCT) were included. Two researchers independently screened studies for inclusion, extracted data, and assessed the methodological quality. A meta‐analysis was conducted using RevMan 5.3 software provided by Cochrane Assisted Network. Results A total of 932 patients underwent THA. There were 467 cases in group DAA and 465 cases in group PA. There was a significant difference in the incidence of lateral femoral cutaneous nerve injury between DAA and PA groups (RR = 38.97, 95% CI: 7.89–192.57, P < 0.05). DAA was associated with less pain compared with PA [WMD = −0.65, 95% CI (−0.91–0.38), P < 0.05]. There was no significant difference in operation time, hospitalization stay, and intraoperative bleeding volume. Moreover, in supplementary data, the number of acetabular prostheses in Lewinnek's safety zones in DAA was more than that in the PA group (RR = 1.20, 95% CI [1.04–1.39], P < 0.05), and the time of discontinuation of walking aids in the DAA group was earlier than that in the PA group (WMD = −11.05, 95% CI [−17.79–4.31], P < 0.05). Conclusion The DAA total hip arthroplasty has comparable results with PA, with earlier postoperative functional recovery, less postoperative pain scores, and higher incidence of lateral femoral cutaneous nerve injury. The results need to be validated by large‐sample, high‐quality RCT studies, and long‐term follow‐up of complications.

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Section: Data Extraction and Synthesismentioning

confidence: 99%

Direct Anterior Approach Versus Posterolateral Approach in Total Hip Arthroplasty: A Systematic Review and Meta‐analysis of Randomized Controlled Studies

Yang

Huang

et al. 2020

Orthopaedic Surgery

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“…Cerebral vasospasm is a difficult pathological entity to treat or to deal with it and also in the literature are a lot of studies and trials about the controversies concerning the prevention and the treatment of the cerebral vasospasm that can occur after subarachnoidian hemorrhage (10)(11)(12)(13).…”

Section: Discussionmentioning

confidence: 99%

Drotaverinum – a new modality of prevention and treatment in cerebral vasospasm after subarachoidian hemorrhage?

Kakucs¹,

Berce²,

Tamas-Szora³

et al. 2016

Romanian Neurosurgery

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Aim: This study want to demonstrate the efficaciousness of drotaverinum as a replacer of papaverine in the prevention and treatment of vasospasm. Material and method: In this study were used 20 albino Wistar male rats. Rats were divided in two groups and vasospasm was induced to the both femoral artery and after that irrigation of the femoral arteries with drotaverinum was performed to demonstrate the vasodilatation that can appear (group A). In the group B after the obtaining of vasospasm irrigation of the femoral arteries with saline solution was performed and this group was used as witness. The length of the vessels was measured when was achieved the vasospasm and also before and after the administration of the solutions. Pictures were taken at every step of dissection and solutions administration to can measure the length of arteries before and after the administration of drotaverinum and the saline solution. Results: In all rats was obtained vasospasm at the femoral artery after clipping the artery and after we irrigate with adrenaline. In the group with drotaverinum we obtained the vasodilatation and in the witness group the caliber of the vessels remain the same. The statistical analysis of the data demonstrate a significant differences between the group were was used drotaverinum and the witness group were was used the saline solution (p<0,001). Conclusions: Drotaverinum has a good vasodilatative effect on arteries and he can prevent the apparition of vasospasm and it can even treat vasospasm if occur by producing local vasodilatation and a good circulation in the area where is administrated. This study showed quantitatively that drotaverinum can treat the experimental peripheral vasospasm in rats.

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“…The authors concluded that routine administration could not be recommended [46]. Nevertheless, in a recent metaanalysis, DCI was the only outcome with a statistically significant effect favoring magnesium treatment [47]. This meta-analysis also concluded that prophylactic use of magnesium is not supported by current evidence, as functional outcome was not improved.…”

Section: Subarachnoidal Hemorrhagementioning

confidence: 95%

Postoperative care of the neurosurgical patient

Siegemund

Steiner

2015

Current Opinion in Anaesthesiology

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Prophylactic Magnesium Sulfate for Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Meta-analysis

Cited by 33 publications

References 11 publications

Direct Anterior Approach Versus Posterolateral Approach in Total Hip Arthroplasty: A Systematic Review and Meta‐analysis of Randomized Controlled Studies

Direct Anterior Approach Versus Posterolateral Approach in Total Hip Arthroplasty: A Systematic Review and Meta‐analysis of Randomized Controlled Studies

Drotaverinum – a new modality of prevention and treatment in cerebral vasospasm after subarachoidian hemorrhage?

Postoperative care of the neurosurgical patient

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