Prophylactic laparoscopic cholecystectomy in adult sickle cell disease patients with cholelithiasis: A prospective cohort study

Muroni, Mirko; Loi, Valeria; Lionnet, François; Girot, Robert; Houry, S

doi:10.1016/j.ijsu.2015.07.708

Cited by 32 publications

(32 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The incidence of procedure-related complications was minimal and the vast majority of patients progressed satisfactorily after surgery 7, 8. The surgical approaches used are laparotomy and laparoscopy, with most authors considering the latter safer for patients, with less complications related to surgery, shorter operative time and faster postoperative recovery, as well as a shorter hospital stay 10, 11, 12, 13, 14. However, a study published in the International Journal of Surgery in 2009 found a positive relationship between acute chest syndrome and laparoscopic surgery.…”

Section: Discussionmentioning

confidence: 99%

“…Most experts, similar to in the hematology service at UFTM, do not recommend surgery before symptoms appear. There is evidence that this profile can be clinically managed for long periods,8, 14 so the medical team usually prescribe antispasmodic agents for minor pain and recommend preventative measures such as a low-fat diet for these patients.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Cholelithiasis and its complications in sickle cell disease in a university hospital

Martins

Soares

Vito

et al. 2017

Revista Brasileira de Hematologia e Hemoterapia

View full text Add to dashboard Cite

IntroductionThe clinical manifestations of sickle cell disease are related to the polymerization of hemoglobin S. The chronic hemolysis caused by this condition often causes the formation of gallstones that can migrate and block the common bile duct leading to acute abdomen.ObjectiveThis study aimed to evaluate the profile of patients with sickle cell disease and cholelithiasis.MethodsPatients with sickle cell disease were separated into groups according to the presence or absence of cholelithiasis. Socioepidemiological and clinical characteristics, such as gender, age, use of hydroxyurea and the presence of other hemoglobinopathies were researched in the medical records of patients.ResultsA hundred and seven patients with sickle cell anemia were treated at the institution. Of these, 27 (25.2%) had cholelithiasis. The presence of cholelithiasis was higher in the 11–29 age group than in younger than 11 years and over 29 years. No association was found for the presence of cholelithiasis with gender, use of hydroxyurea or type of hemoglobinopathy (hemoglobin SS, hemoglobin SC or sickle beta-thalassemia). Sixteen of the patients had to be submitted to cholecystectomy with 14 of the surgeries being performed by laparoscopy. Complications were observed in three patients and one patient died for reasons unrelated to the surgery.ConclusionA quarter of patients with sickle cell disease had gallstones, more commonly in the 11- to 29-year age range. Patients should be monitored from childhood to prevent cholelithiasis with preoperative, intra-operative and postoperative care being crucial to reduce the risk of complications in these patients.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Cholelithiasis and its complications in sickle cell disease in a university hospital

Martins

Soares

Vito

et al. 2017

Revista Brasileira de Hematologia e Hemoterapia

View full text Add to dashboard Cite

show abstract

“…One hundred and sixty‐eight reports discuss, in variable detail, the perioperative care of SCD patients. A multidisciplinary collaboration and communication between the surgeon, anesthetist, hematologist and blood bank specialist are universally considered to be mandatory, although specific study data is not available to support this unanimous recommendation . When required, the preemptive and planned coordination with an ICU team for post‐operative admission and care is suggested .…”

Section: Resultsmentioning

confidence: 99%

“…The role for antibioprophylaxis is discussed by many, and two strategies seem to co‐exist in the literature. There are authors recommending prophylaxis according to type of surgery, and others adapting it to the individual patients' medical histories . As a standout, splenectomy needs specific considerations, including preoperative immunizations against encapsulated bacteria, as in the context of asplenia .…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Perioperative care of children with sickle cell disease: A systematic review and clinical recommendations

et al. 2019

View full text Add to dashboard Cite

Children with sickle cell disease (SCD) require specific perioperative care, and clinical practice in this area remains poorly defined. We aimed to conduct a systematic, PRISMA-based review of the literature, available clinical guidelines and practice recommendations. We also aimed to extract any valuable information for the "best of available-evidence"-based prevention of perioperative adverse events in children with SCD, and highlight the most urgent priorities in clinical research. As data sources, USWe also included institutional, consortia and expert group guidelines. Included were reports/guidelines in English, French, German, and Italian. Excluded were reports on obstetrical and fetal management. We identified 202 reports/guidelines fulfilling the criteria outlined above. A majority focused on visceral, cardiovascular and orthopedic surgery procedures, and only five were multicenter randomized controlled trials and two prospective randomized studies. After grading of the quality of the evidence, the extracted data was summarized into clinical recommendations for daily practice. Additionally, we designed a risk-grading algorithm to identify contexts likely to be associated with adverse outcomes. In conclusion, we provide a systematic PRISMA-based review of the existing literature and ancillary practice and delineate a set of clinical recommendations and priorities for research.

show abstract

Correlates of gallbladder stones among patients with sickle cell disease: A meta‐analysis

et al. 2021

View full text Add to dashboard Cite

Sickle cell disorders are the most common hemoglobinopathies worldwide. Clinical variability of sickle cell disease (SCD) and susceptibility to its complications have been attributed to hematologic, genetic, and other influencing factors. This review aimed to provide further summary and analyses of the prevalence and factors associated with cholelithiasis among patients with SCD. A systematic database search was conducted in MEDLINE (PubMed), ScienceDirect, Google Scholar, World Health Organization Virtual Health Library, Cochrane Library databases, and System for Information on Gray Literature in Europe (SIGLE). Pooled prevalence, odds ratio (OR), and standardized mean difference (SMD) with the corresponding 95% confidence interval (CI) were calculated using Comprehensive Meta‐Analysis Software version 3.3. A total of 34 studies that fulfilled the eligibility criteria were included in the analyses. The overall prevalence of cholelithiasis among SCD patients was 25.3% (95% CI 19.4–32.3%). The risk of developing cholelithiasis was significantly associated with lower total hemoglobin level (SMD = −0.45; P = 0.002), lower hemoglobin F (HbF) level (SMD = −0.85; P = 0.003), higher total serum bilirubin level (SMD = 1.15; P < 0.001), higher reticulocytes count (SMD = 0.44; P = 0.007), and UDP‐glucuronosyltransferase‐1A1 enzyme (UGT1A1) promoter polymorphism. This review provides a comprehensive view of the high rate of cholelithiasis and its associated factors in SCD patients.

show abstract

Prophylactic laparoscopic cholecystectomy in adult sickle cell disease patients with cholelithiasis: A prospective cohort study

Cited by 32 publications

References 29 publications

Cholelithiasis and its complications in sickle cell disease in a university hospital

Cholelithiasis and its complications in sickle cell disease in a university hospital

Perioperative care of children with sickle cell disease: A systematic review and clinical recommendations

Correlates of gallbladder stones among patients with sickle cell disease: A meta‐analysis

Contact Info

Product

Resources

About