Prophylactic Intravenous Administration of Caffeine and Recovery After Ambulatory Surgical Procedures

Weber, J.; Klindworth, Jacinta T.; Arnold, Jacqueline J.; Danielson, David R.; Ereth, Mark H.

doi:10.4065/72.7.621

Cited by 13 publications

(7 citation statements)

References 11 publications

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“…It can be associated with a number of adverse effects including thirst, hunger, dizziness, nausea, vomiting, headache, dehydration, and hypoglycemia (Doze & White, 1987; Smith et al, 1997; Yogendran, Asokumar, Cheng, & Chang, 1995). In addition, prolonged fasting can be associated with headache and other caffeine withdrawal discomforts in individuals who usually have coffee, tea, or another caffeinated beverage in the morning (Weber, Ereth, & Danielson, 1993; Weber, Klindworth, Arnold, Danielson, & Ereth, 1997). Shortening fasting durations can prevent or minimize these adverse responses.…”

Section: Discussionmentioning

confidence: 99%

Actual Versus Instructed Fasting Times and Associated Discomforts in Women Having Scheduled Cesarean Birth

Winslow

2006

Journal of Obstetric, Gynecologic & Neonatal Nursing

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Section: Discussionmentioning

confidence: 99%

Actual Versus Instructed Fasting Times and Associated Discomforts in Women Having Scheduled Cesarean Birth

Winslow

2006

Journal of Obstetric, Gynecologic & Neonatal Nursing

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“…There were 10 studies investigating the effect of caffeine peri-operatively and the development of post-operative headache [24][25][26][27][28][29][30][31][32][33] . Seven investigated caffeine withdrawal [24][25][26][27][28][29][30][31][32][33] and three studies administered oral caffeine to prevent post-operative headache [31][32][33] . Of the seven prospective studies investigating the effect of caffeine withdrawal, ve studies found caffeine withdrawal increased the incidence of post-operative headache [24][25][26][27][28][29][30][31][32][33] .…”

Section: Caffeine Use In the Peri-operative Periodmentioning

confidence: 99%

“…Seven investigated caffeine withdrawal [24][25][26][27][28][29][30][31][32][33] and three studies administered oral caffeine to prevent post-operative headache [31][32][33] . Of the seven prospective studies investigating the effect of caffeine withdrawal, ve studies found caffeine withdrawal increased the incidence of post-operative headache [24][25][26][27][28][29][30][31][32][33] . Three studies investigated the administration of caffeine to relieve post-operative headache [31][32][33] .…”

Section: Caffeine Use In the Peri-operative Periodmentioning

confidence: 99%

“…Of the seven prospective studies investigating the effect of caffeine withdrawal, ve studies found caffeine withdrawal increased the incidence of post-operative headache [24][25][26][27][28][29][30][31][32][33] . Three studies investigated the administration of caffeine to relieve post-operative headache [31][32][33] .…”

Section: Caffeine Use In the Peri-operative Periodmentioning

confidence: 99%

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Use of Therapeutic Caffeine in Acute Care Post-operative and Critical Care Settings: a Scoping Review

Bright¹,

Raman

Laupland

2020

Preprint

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BackgroundCaffeine is the most utilised psychoactive drug worldwide. However, caffeine withdrawal and the therapeutic use of caffeine in intensive care and in the peri-operative period have not been well summarised. Our objective was to conduct a scoping review of caffeine withdrawal and use in the intensive care unit (ICU) and post-operative patients. MethodsPubMed, Embase, CINAHL Complete, Scopus and Web of Science were systematically searched for studies investigating the effects of caffeine withdrawal or administration in ICU patients and in the peri-operative period. Areas of recent systematic review such as pain or post-dural puncture headache were not included in this review. Studies were limited to adults. ResultsOf 2268 articles screened, 26 were included and grouped into two themes of caffeine use in in the peri-operative period and in the ICU. Caffeine withdrawal in the post-operative period increases the incidence of headache, which can be effectively treated prophylactically with peri-operative caffeine. There were no studies investigating caffeine withdrawal or effect on sleep wake cycles, daytime somnolence, or delirium in the intensive care setting. Administration of caffeine results in faster emergence from sedation and anaesthesia, particularly in individuals who are at high risk of post-extubation complications. There has only been one study investigating caffeine administration to facilitate post-anaesthetic emergence in ICU. Caffeine administration appears to be safe in moderate doses in the peri-operative period and in the intensive care setting. ConclusionsAlthough caffeine is widely used, there is a paucity of studies investigating withdrawal or therapeutic effects in patients admitted to ICU and further novel studies are a priority.

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“…A murine model found caffeine expedites recovery following both isoflurane-and propofol-based anesthetics [4]. Caffeine administration has been shown to decrease symptoms of acute caffeine withdrawal during anesthetic recovery [5], but otherwise has not been well studied if it can hasten anesthetic recovery. At our institution, several practitioners have developed an informal practice of administering intravenous caffeine to heavily sedated patients in the post-anesthesia care unit (PACU).…”

Section: Introductionmentioning

confidence: 99%

Effects of caffeine administration on sedation and respiratory parameters in patients recovering from anesthesia

Warner

Schroeder

et al. 2018

Bosn J of Basic Med Sci

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Caffeine has been shown to enhance the speed of recovery from general anesthesia in murine models, though data in human patients is lacking. This is a retrospective review of intravenous caffeine administration (median dose 150 [125, 250] mg) to 151 heavily sedated patients in the post-anesthesia recovery area, to determine the association between caffeine administration and changes in sedation score, respiratory rate, and oxyhemoglobin saturation. Richmond Agitation-Sedation Scale (RASS) score, respiratory rate, and oxyhemoglobin saturation values were obtained during the 90-minute period prior to and following caffeine administration. Generalized estimating equations (GEE) with explanatory variables of time, caffeine, and the time-by-caffeine interaction were created to assess changes in the variables of interest after caffeine administration. Following the administration of caffeine, the RASS scores increased (estimate = 0.57, SE = 0.14, p < 0.001) but a trend over time or in the interaction effect was not observed, suggesting that the changes in RASS were not solely due to the recovery from anesthesia over time. No association was found between caffeine administration and changes in respiratory parameters. No adverse cardiac events were observed. Our data suggests that intravenous caffeine may enhance the speed of recovery following general anesthesia, though future prospective trials are necessary to define the optimal dose and timing of administration.

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Prophylactic Intravenous Administration of Caffeine and Recovery After Ambulatory Surgical Procedures

Cited by 13 publications

References 11 publications

Actual Versus Instructed Fasting Times and Associated Discomforts in Women Having Scheduled Cesarean Birth

Actual Versus Instructed Fasting Times and Associated Discomforts in Women Having Scheduled Cesarean Birth

Use of Therapeutic Caffeine in Acute Care Post-operative and Critical Care Settings: a Scoping Review

Effects of caffeine administration on sedation and respiratory parameters in patients recovering from anesthesia

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