Prophylactic Intravenous Administration of Caffeine and Recovery After Ambulatory Surgical Procedures

Weber, J.; Klindworth, Jacinta T.; Arnold, Jacqueline J.; Danielson, David R.; Ereth, Mark H.

doi:10.1016/s0025-6196(11)63567-2

Cited by 23 publications

(11 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, premorbid primary headache syndromes, even in otherwise solid papers (74), are seldom reported. It seems though that subjects with a history of frequent headaches (75) are at increased risk, and that migraineurs and subjects who experience withdrawal headache share some comorbidity such as major depression and anxiety (5). To “produce experimental headaches which would be more physiological than experimental histamine and nitrite headaches,” Dreisbach in 1940 gave a number of non-habitual coffee drinkers capsules of 10–12 grains (650–780 mg) of caffeine daily for 1 week and then withdrew the treatment.…”

Section: Resultsmentioning

confidence: 99%

Caffeine and Primary (Migraine) Headaches—Friend or Foe?

Alstadhaug

Andreou

2019

Front. Neurol.

View full text Add to dashboard Cite

Background: The actions of caffeine as an antagonist of adenosine receptors have been extensively studied, and there is no doubt that both daily and sporadic dietary consumption of caffeine has substantial biological effects on the nervous system. Caffeine influences headaches, the migraine syndrome in particular, but how is unclear.Materials and Methods: This is a narrative review based on selected articles from an extensive literature search. The aim of this study is to elucidate and discuss how caffeine may affect the migraine syndrome and discuss the potential pathophysiological pathways involved.Results: Whether caffeine has any significant analgesic and/or prophylactic effect in migraine remains elusive. Neither is it clear whether caffeine withdrawal is an important trigger for migraine. However, withdrawal after chronic exposure of caffeine may cause migraine-like headache and a syndrome similar to that experienced in the prodromal phase of migraine. Sensory hypersensitivity however, does not seem to be a part of the caffeine withdrawal syndrome. Whether it is among migraineurs is unknown. From a modern viewpoint, the traditional vascular explanation of the withdrawal headache is too simplistic and partly not conceivable. Peripheral mechanisms can hardly explain prodromal symptoms and non-headache withdrawal symptoms. Several lines of evidence point at the hypothalamus as a locus where pivotal actions take place.Conclusion: In general, chronic consumption of caffeine seems to increase the burden of migraine, but a protective effect as an acute treatment or in severely affected patients cannot be excluded. Future clinical trials should explore the relationship between caffeine withdrawal and migraine, and investigate the effects of long-term elimination.

show abstract

Section: Resultsmentioning

confidence: 99%

Caffeine and Primary (Migraine) Headaches—Friend or Foe?

Alstadhaug

Andreou

2019

Front. Neurol.

View full text Add to dashboard Cite

show abstract

“…Moreover, the nonspecific adenosine receptor antagonist caffeine has been suggested for the prevention or treatment of postdural puncture headache 13. While this indication has been challenged, 13 caffeine remains an important therapeutic agent in the treatment or prevention of caffeine withdrawal headache in perioperative patients 14,15. Similarly, the non-specific adenosine receptor antagonist theophylline has been used in the past for treating obstructive airway disease, but has been replaced by inhaled long-acting beta-agonist bronchodilators due to less drug-drug interactions and toxicity from drug overdosing 16…”

Section: Introductionmentioning

confidence: 99%

Adenosine: An Old Drug Newly Discovered

Eltzschig

Warner²,

Warner³

2009

Anesthesiology

224

238

View full text Add to dashboard Cite

Over decades, anesthesiologists have used intravenous adenosine as mainstay therapy for diagnosing or treating supraventricular tachycardia in the perioperative setting. More recently, specific adenosine receptor therapeutics or gene-targeted mice deficient in extracellular adenosine production or individual adenosine receptors became available. These models enabled physicians and scientists to learn more about the biological functions of extracellular nucleotide metabolism and adenosine signaling. Such functions include specific signaling effects through adenosine receptors expressed by many mammalian tissues, for example vascular endothelia, myocytes, heptocytes, intestinal epithelia or immune cells. At present, pharmacological approaches to modulate extracellular adenosine signaling are evaluated for their potential use in perioperative medicine, including attenuation of acute lung injury, renal, intestinal, hepatic and myocardial ischemia, or vascular leakage. If these laboratory studies can be translated into clinical practice, adenosine receptor based therapeutics may become an integral pharmacological component of daily anesthesiology practice.

show abstract

“…There were 10 studies investigating the effect of caffeine peri-operatively and the development of post-operative headache [24][25][26][27][28][29][30][31][32][33] . Seven investigated caffeine withdrawal [24][25][26][27][28][29][30][31][32][33] and three studies administered oral caffeine to prevent post-operative headache [31][32][33] . Of the seven prospective studies investigating the effect of caffeine withdrawal, ve studies found caffeine withdrawal increased the incidence of post-operative headache [24][25][26][27][28][29][30][31][32][33] .…”

Section: Caffeine Use In the Peri-operative Periodmentioning

confidence: 99%

Use of Therapeutic Caffeine in Acute Care Post-operative and Critical Care Settings: a Scoping Review

Bright¹,

Raman

Laupland

2020

Preprint

View full text Add to dashboard Cite

BackgroundCaffeine is the most utilised psychoactive drug worldwide. However, caffeine withdrawal and the therapeutic use of caffeine in intensive care and in the peri-operative period have not been well summarised. Our objective was to conduct a scoping review of caffeine withdrawal and use in the intensive care unit (ICU) and post-operative patients. MethodsPubMed, Embase, CINAHL Complete, Scopus and Web of Science were systematically searched for studies investigating the effects of caffeine withdrawal or administration in ICU patients and in the peri-operative period. Areas of recent systematic review such as pain or post-dural puncture headache were not included in this review. Studies were limited to adults. ResultsOf 2268 articles screened, 26 were included and grouped into two themes of caffeine use in in the peri-operative period and in the ICU. Caffeine withdrawal in the post-operative period increases the incidence of headache, which can be effectively treated prophylactically with peri-operative caffeine. There were no studies investigating caffeine withdrawal or effect on sleep wake cycles, daytime somnolence, or delirium in the intensive care setting. Administration of caffeine results in faster emergence from sedation and anaesthesia, particularly in individuals who are at high risk of post-extubation complications. There has only been one study investigating caffeine administration to facilitate post-anaesthetic emergence in ICU. Caffeine administration appears to be safe in moderate doses in the peri-operative period and in the intensive care setting. ConclusionsAlthough caffeine is widely used, there is a paucity of studies investigating withdrawal or therapeutic effects in patients admitted to ICU and further novel studies are a priority.

show abstract

Prophylactic Intravenous Administration of Caffeine and Recovery After Ambulatory Surgical Procedures

Cited by 23 publications

References 11 publications

Caffeine and Primary (Migraine) Headaches—Friend or Foe?

Caffeine and Primary (Migraine) Headaches—Friend or Foe?

Adenosine: An Old Drug Newly Discovered

Use of Therapeutic Caffeine in Acute Care Post-operative and Critical Care Settings: a Scoping Review

Contact Info

Product

Resources

About