Prophylactic Compared With Therapeutic Ibuprofen Analgesia in First-Trimester Medical Abortion

Raymond, Elizabeth G.; Weaver, Mark A.; Louie, Karmen S.; Dean, Gillian; Porsch, Lauren; Lichtenberg, E. Steve; Ali, Rose; Arnesen, Michelle

doi:10.1097/aog.0b013e31829d5a33

Cited by 44 publications

(46 citation statements)

References 14 publications

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“…Notwithstanding, the high level of pain reported on the visual analog scale and the relatively high proportion of women who reported pain being greater than they expected indicates that there may be room for improved pain management. There is little consensus about the most efficacious pain relief regimen for first‐trimester medical abortion and research is continuing to inform service delivery practice on pain management [13].…”

Section: Discussionmentioning

confidence: 99%

Efficacy and acceptability of a mifepristone-misoprostol combined regimen for early induced abortion among women in Mexico City

Peña

Dzuba

Smith³

et al. 2014

International Journal of Gynecology & Obstetrics

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Section: Discussionmentioning

confidence: 99%

Efficacy and acceptability of a mifepristone-misoprostol combined regimen for early induced abortion among women in Mexico City

Peña

Dzuba

Smith³

et al. 2014

International Journal of Gynecology & Obstetrics

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“…The woman should be sent home with appropriate instructions for analgesia with over-the-counter medications and can be provided with prescriptions for oral narcotics to use when needed. One randomized trial found that multiple doses of ibuprofen given prophylactically at the time of misoprostol administration did not significantly reduce pain associated with medical abortion compared with ibuprofen taken when needed (51). One randomized trial found that ibuprofen taken when needed was more effective than acetaminophen to reduce pain associated with medical abortion (49).…”

Section: Medical Abortion Versus Surgical Abortionmentioning

confidence: 99%

Practice Bulletin No. 143

2014

Obstetrics &Amp; Gynecology

107

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Over the past three decades, medical methods of abortion have been developed throughout the world and are now a standard method of providing abortion care in the United States. Medical abortion, which involves the use of medications rather than a surgical procedure to induce an abortion, is an option for women who wish to terminate a first-trimester pregnancy. Although the method is most commonly used up to 63 days of gestation (calculated from the first day of the last menstrual period), the treatment also is effective after 63 days of gestation. The Centers for Disease Control and Prevention estimates that 64% of abortions are performed before 63 days of gestation (1). Medical abortions currently comprise 16.5% of all abortions in the United States and 25.2% of all abortions at or before 9 weeks of gestation (1). Mifepristone, combined with misoprostol, is the most commonly used medical abortion regimen in the United States and Western Europe; however, in parts of the world, mifepristone remains unavailable. This document presents evidence of the effectiveness, benefits, and risks of first-trimester medical abortion and provides a framework for counseling women who are considering medical abortion.

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“…18 Several studies have 41 Medical Abortion for Clinical Practice & CME Review Article evaluated first-trimester medical abortion beyond 63 days' gestation. Three studies done in Europe found high success rates, but for each of these, the women were hospitalized for the abortion procedure.…”

Section: Gestational Age Limitsmentioning

confidence: 99%

“…A recent study of 250 women undergoing medical abortion did not show any benefit to taking ibuprofen before the onset of pain from medical abortion, as opposed to taking it after the onset of pain. 41 Although commonly prescribed, and apparently needed by most women undergoing medical abortion, no studies have evaluated opioid analgesics agents in comparison to ibuprofen to determine their efficacy for pain relief.…”

Section: Troubleshootingmentioning

confidence: 99%

An Overview of Medical Abortion for Clinical Practice

Bryant¹,

Regan²,

Stuart³

2014

Obstetrical &Amp; Gynecological Survey

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Medical abortion is a safe, convenient, and effective method for terminating an early unintended pregnancy. Medical abortion can be performed up to 63 days from the last menstrual period and may even be used up to 70 days for women who prefer medical abortion over surgical abortion. Counseling on the adverse effects and expectations for medical abortion is critical to success. Medical abortion can be performed in a clinic without special equipment, and it is perceived as more "natural" than a surgical abortion by many women. Follow-up for medical abortion can be simplified to include only serum human chorionic gonadotropin measurements when necessary, although obtaining an ultrasound remains the criterion standard. Pain associated with medical abortion is best treated with nonsteroidal anti-inflammatory medications, possibly in combination with opioid analgesics. Medical abortion can contribute to continuity of care for women who wish to remain with their primary care providers for management of their abortion.

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Prophylactic Compared With Therapeutic Ibuprofen Analgesia in First-Trimester Medical Abortion

Abstract: I.

Cited by 44 publications

References 14 publications

Efficacy and acceptability of a mifepristone-misoprostol combined regimen for early induced abortion among women in Mexico City

Efficacy and acceptability of a mifepristone-misoprostol combined regimen for early induced abortion among women in Mexico City

Practice Bulletin No. 143

An Overview of Medical Abortion for Clinical Practice

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