Prophylactic antibiotics and surgery for primary clefts

Smyth, A.G.; Knepil, G.J.

doi:10.1016/j.bjoms.2007.07.207

Cited by 33 publications

(27 citation statements)

References 9 publications

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“…13 Our results suggest that postoperative antibiotics have no role in cleft lip surgery. Consequently, our results indicate that a standardized patient education program can be an efficient way of reducing complications in terms of postoperative lip infections in this environment.…”

Section: Discussionmentioning

confidence: 68%

Lessons Learned From Two Consecutive Cleft Lip and Palate Missions and the Impact of Patient Education

Schönmeyr¹,

Restrepo²,

Wendby³

et al. 2014

Journal of Craniofacial Surgery

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Two consecutive cleft missions were conducted in Guwahati, northeastern India in December 2010 and January 2011. In the later mission, a standardized patient education program for postoperative care was introduced. The objective of this study was to retrospectively evaluate the impact of the patient education program on cleft lip complications in terms of wound infection and dehiscence. Two hundred ninety-eight cleft lip repairs were performed in the first mission and 220 (74%) returned for early follow-up. In the second mission, 356 patients were operated on and 252 (71%) returned for follow-up. From the first mission, 8 patients (3.7%) were diagnosed with lip wound infection and 21 patients (9.6%) with lip dehiscence. After the second mission, only 1 patient (0.4%) returned with a wound infection and 16 (6.4%) were diagnosed with dehiscence.Using binary logistic regression including age, cleft type, postoperative antibiotics, surgeon, and patient education program as covariates, the patient education program stood out as the only variable with a statistically significant impact on the incidence of postoperative wound infections. Even though the incidence of lip dehiscence was reduced by one third when the patient education program was utilized, our regression model singled out the surgeons as the only factor significantly related to this type of complication. Moreover, no benefits of postoperative antibiotic prophylaxis were found. Further analysis of the data also implied that the use of tissue adhesive as a compliment to sutures does not reduce the risk of dehiscence.

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Section: Discussionmentioning

confidence: 68%

Lessons Learned From Two Consecutive Cleft Lip and Palate Missions and the Impact of Patient Education

Schönmeyr¹,

Restrepo²,

Wendby³

et al. 2014

Journal of Craniofacial Surgery

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“…There is no consensus among surgeons regarding the use of antimicrobial prophylaxis in the repair of cleft lip and palate. 1074 The occurrence of postoperative infections after these procedures is 1.3%. 1075 No controlled trials have evaluated the use of antimicrobial prophylaxis in these procedures.…”

Section: Plastic Surgery and Breast Proceduresmentioning

confidence: 99%

Clinical practice guidelines for antimicrobial prophylaxis in surgery

Bratzler

Dellinger

Olsen

et al. 2013

American Journal of Health-System Pharmacy

1,832

1,464

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“…There is no consensus among surgeons regarding the use of antimicrobial prophylaxis in the repair of cleft lip and palate [1074]. The occurrence of postoperative infections after these procedures is 1.3% [1075].…”

Section: Surgical Prophylaxis Guidelinesmentioning

confidence: 99%

Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery

Bratzler

Dellinger

Olsen

et al. 2013

Surgical Infections

1,169

1,225

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T hese guidelines were developed jointly by the American Society of Health-System Pharmacists (ASHP), the Infectious Diseases Society of America (IDSA), the Surgical Infection Society (SIS), and the Society for Healthcare Epidemiology of America (SHEA). This work represents an update to the previously published ASHP Therapeutic Guidelines on Antimicrobial Prophylaxis in Surgery [1], as well as guidelines from IDSA and SIS [2,3]. The guidelines are intended to provide practitioners with a standardized approach to the rational, safe, and effective use of antimicrobial agents for the prevention of surgical site infections (SSIs) based on currently available clinical evidence and emerging issues. Prophylaxis refers to the prevention of an infection and can be characterized as primary prophylaxis, secondary prophylaxis, or eradication. Primary prophylaxis refers to the prevention of an initial infection. Secondary prophylaxis refers to the prevention of recurrence or reactivation of a preexisting infection. Eradication refers to the elimination of a colonized organism to prevent the development of an infection. These guidelines focus on primary perioperative prophylaxis. Guidelines development and use Members of ASHP, IDSA, SIS, and SHEA were appointed to serve on an expert panel established to ensure the validity, reliability, and utility of the revised guidelines. The work of the panel was facilitated by faculty of the

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Prophylactic antibiotics and surgery for primary clefts

Cited by 33 publications

References 9 publications

Lessons Learned From Two Consecutive Cleft Lip and Palate Missions and the Impact of Patient Education

Lessons Learned From Two Consecutive Cleft Lip and Palate Missions and the Impact of Patient Education

Clinical practice guidelines for antimicrobial prophylaxis in surgery

Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery

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