Prophylactic Antibiotics and Postoperative Endophthalmitis

Retracted: Epidemiological evaluation of intraoperative antibiosis as a protective agent against endophthalmitis after cataract surgery

“…This survey revealed some promising results both concerning incision techniques [9][10][11][12][13] as well as the impact of antibiotic prophylaxis. 9,[14][15][16][17][18][19][20] According to the surgeons' self-reported data in this survey the sclerocorneal incision was associated with a 65% reduction in risk for endophthalmitis when compared to the clear cornea approach. Furthermore, the intraocular application of antibiotics showed a 35% reduction in endophthalmitis risk.…”

Intracameral cefuroxime injection at the end of cataract surgery to reduce the incidence of endophthalmitis: French study

“…8,12 Subconjunctival antibiotic injection has been abandoned for pharmacokinetic reasons. [13][14][15][16][17][18] Systemic antibiotic prophylaxis is reserved for high-risk cases. 16,[19][20][21] Antibiotic supplementation of the infusion fluid fails to decrease contamination of the anterior chamber and therefore is no longer accepted as a worthy method for preventing postoperative infection.…”

Bacterial Flora in Relation to Cataract Extraction

“…After the introduction of antibiotics, the same line was followed by topical administration prior to ocular surgery (Dunnington & Locatcher-Khorazo 1945, Hughes & Owens 1947, Dellaporta et al 1949, Locatcher-Khorazo 1953, Callahan 1953. However, in later years, with the experience gained from general surgery, some authors (Leopold 1958, Leopold & Apt 1960, Kolker et al 1967 1) doubted the prophylactic role of antibiotics before surgery and warned of the danger of altering the local conjunctival flora, thus permitting the development of pathogens which flourish only because competitive organisms have been inhibited. Consequently, many surgeons today either use no antibiotic prophylaxis prior to surgery (Chalkley 1963, Hallermann 1963, Nolan 1967, Constantaras et al 1972, Jaffe 1972, or compromise by giving a single dose pre-or peroperatively (Aronstam 1964.…”