“…At present, existing scholarship has dedicated very little attention to the local political, economic, and social factors that shape the fight against COVID-19, which is surprising, as scholars have highlighted the political economy of recent epidemics, including COVID-19 [ 21 , 22 , 23 , 24 , 25 , 26 , 27 ]. Sanders and colleagues, for example, stressed the economic and political forces that have contributed to the severe weakness of health systems of West African countries which were seriously affected by the Ebola virus [ 23 ], and COVID-19 highlights the need to take inequality and social stratification in Africa seriously [ 28 ]. This paper adds to this emerging research stream by analysing the political economy of the COVID-19 pandemic in Cameroon and addressing two core questions: (a) What are the economic and political roots of Cameroon’s weak health care system?…”