Properties of cross-modal occipital responses in early blindness: An ALE meta-analysis

Zhang, Caiyun; Lee, Tatia M.C.; Fu, Yunwei; Ren, Chaoran; Chan, Che Hin Chetwyn; Tao, Qian

doi:10.1016/j.nicl.2019.102041

Cited by 16 publications

(32 citation statements)

References 130 publications

(188 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In another work, Stam et al 45 proposed two types of network re-organization such that in the acute phase there is a shift from local to global processing, whereas the opposite occurs in the chronic phase. This would be consistent with reports of low modularity in the acute post-stroke phase followed by increased modularity at later post-stroke time-points 12 or in response to treatment 11 , 13 . These observations underscore that future simulation work and network analyses of simulated and real lesions will need to investigate the dynamic long-term changes that are triggered by the focal lesion and the initial node subtraction.…”

Section: Discussionsupporting

confidence: 92%

“…We identified a “reference” modular organization which was used in calculating the graph-theoretic properties that were evaluated in subsequent analyses. This modular organization was reported previously in 13 . Briefly, it was derived by applying hierarchical clustering (agglomerative) with Ward's criterion implemented in SciPy ( https://scipy.org ) to the averaged correlation matrix of the HC Group.…”

Section: Methodssupporting

confidence: 86%

“…The participants were administered an extensive battery of cognitive and language tests. Prior reports on subsets of these individuals include 13 , 38 , 39 .…”

Section: Methodsmentioning

confidence: 99%

“…FMRI data preprocessing and functional connectivity estimation (see “ Functional connectivity estimation ”) were identical to our previous study 13 . Functional data were preprocessed with FEAT in FSL 5.0.9 40 with the following pre-processing steps: removal of the first 4 volumes of each run, motion correction with MCFLIRT, slice-timing correction, non-brain tissue removal with BET, spatial smoothing using a 5 mm FWHM Gaussian kernel, grand-mean intensity normalization, high-pass temporal filtering (0.01 Hz).…”

Section: Methodsmentioning

confidence: 99%

“… 7 – 10 ). In addition, these approaches have also been applied to understanding the neuroplasticity that supports recovery of function after neural damage 11 – 13 ; for reviews also see 14 – 16 . In the context of focal lesions, a number of computer simulation studies have been directed at developing a better quantitative understanding of the effects of focal lesions on the brain’s network organization.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Investigating the network consequences of focal brain lesions through comparisons of real and simulated lesions

Tao

Rapp

2021

Sci Rep

View full text Add to dashboard Cite

Given the increased interest in the functional human connectome, a number of computer simulation studies have sought to develop a better quantitative understanding of the effects of focal lesions on the brain’s functional network organization. However, there has been little work evaluating the predictions of this simulation work vis a vis real lesioned connectomes. One of the few relevant studies reported findings from real chronic focal lesions that only partially confirmed simulation predictions. We hypothesize that these discrepancies arose because although the effects of focal lesions likely consist of two components: short-term node subtraction and long-term network re-organization, previous simulation studies have primarily modeled only the short-term consequences of the subtraction of lesioned nodes and their connections. To evaluate this hypothesis, we compared network properties (modularity, participation coefficient, within-module degree) between real functional connectomes obtained from chronic stroke participants and “pseudo-lesioned” functional connectomes generated by subtracting the same sets of lesioned nodes/connections from healthy control connectomes. We found that, as we hypothesized, the network properties of real-lesioned connectomes in chronic stroke differed from those of the pseudo-lesioned connectomes which instantiated only the short-term consequences of node subtraction. Reflecting the long-term consequences of focal lesions, we found re-organization of the neurotopography of global and local hubs in the real but not the pseudo-lesioned connectomes. We conclude that the long-term network re-organization that occurs in response to focal lesions involves changes in functional connectivity within the remaining intact neural tissue that go well beyond the short-term consequences of node subtraction.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Methodssupporting

confidence: 86%

“…The participants were administered an extensive battery of cognitive and language tests. Prior reports on subsets of these individuals include 13 , 38 , 39 .…”

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Investigating the network consequences of focal brain lesions through comparisons of real and simulated lesions

Tao

Rapp

2021

Sci Rep

View full text Add to dashboard Cite

show abstract

Enhanced maternal behaviors in a mouse model of congenital blindness

Bouguiyoud

Xie

Bronchti

et al. 2023

Developmental Psychobiology

View full text Add to dashboard Cite

In mammals, mothering is one of the most important prosocial female behavior to promote survival, proper sensorimotor, and emotional development of the offspring. Different intrinsic and extrinsic factors can initiate and maintain these behaviors, such as hormonal, cerebral, and sensory changes. Infant cues also stimulate multisensory systems and orchestrate complex maternal responsiveness. To understand the maternal behavior driven by complex sensory interactions, it is necessary to comprehend the individual sensory systems by taking out other senses. An excellent model for investigating sensory regulation of maternal behavior is a murine model of congenital blindness, the ZRDBA mice, where both an anophthalmic and sighted mice are generated from the same litter. Therefore, this study aims to assess whether visual inputs are essential to driving maternal behaviors in mice. Maternal behaviors were assessed using three behavioral tests, including the pup retrieval test, the home cage maternal behavior test, and the maternal aggression test. Our results show that blind mothers (1) took less time to retrieve their offspring inside the nest, (2) spent more time nursing and licking their offspring in the second‐ and third‐week postpartum, and (3) exhibited faster aggressive behaviors when exposed to an intruder male, compared to the sighted counterparts. This study provides evidence that congenitally blind mothers show more motivation to retrieve the pups, care, and protection towards their pups than sighted ones, likely due to a phenomenon of sensory compensation.

show abstract

Social cognition in the blind brain: A coordinate‐based meta‐analysis

Arioli

Ricciardi

Cattaneo

2020

Human Brain Mapping

View full text Add to dashboard Cite

Social cognition skills are typically acquired on the basis of visual information (e.g., the observation of gaze, facial expressions, gestures). In light of this, a critical issue is whether and how the lack of visual experience affects neurocognitive mechanisms underlying social skills. This issue has been largely neglected in the literature on blindness, despite difficulties in social interactions may be particular salient in the life of blind individuals (especially children). Here we provide a meta‐analysis of neuroimaging studies reporting brain activations associated to the representation of self and others' in early blind individuals and in sighted controls. Our results indicate that early blindness does not critically impact on the development of the “social brain,” with social tasks performed on the basis of auditory or tactile information driving consistent activations in nodes of the action observation network, typically active during actual observation of others in sighted individuals. Interestingly though, activations along this network appeared more left‐lateralized in the blind than in sighted participants. These results may have important implications for the development of specific training programs to improve social skills in blind children and young adults.

show abstract

Properties of cross-modal occipital responses in early blindness: An ALE meta-analysis

Cited by 16 publications

References 130 publications

Investigating the network consequences of focal brain lesions through comparisons of real and simulated lesions

Investigating the network consequences of focal brain lesions through comparisons of real and simulated lesions

Enhanced maternal behaviors in a mouse model of congenital blindness

Social cognition in the blind brain: A coordinate‐based meta‐analysis

Contact Info

Product

Resources

About