Properties of bacterial cellulose produced in a pilot-scale spherical type bubble column bioreactor

Choi, Chang Nam; Song, Hyo Jeong; Kim, Myong Jun; Chang, Mi Hwa; Kim, Seong Jun

doi:10.1007/s11814-009-0021-1

Cited by 34 publications

(12 citation statements)

References 13 publications

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“…Stirred-tank and air-lift reactors are the most commonly used bioreactors for BNC generation under agitated cultivation conditions [62]. Successful pilot-scale production under agitated conditions was demonstrated by Song and colleagues using a 50-L modified airlift-type bubble column bioreactor and utilizing saccharified food waste as feedstock [63].…”

Section: Research: Reviewmentioning

confidence: 99%

Nanocellulose as a natural source for groundbreaking applications in materials science: Today’s state

et al. 2018

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Nanocelluloses are natural materials with at least one dimension in the nano-scale. They combine important cellulose properties with the features of nanomaterials and open new horizons for materials science and its applications. The field of nanocellulose materials is subdivided into three domains: biotechnologically produced bacterial nanocellulose hydrogels, mechanically delaminated cellulose nanofibers, and hydrolytically extracted cellulose nanocrystals. This review article describes today's state regarding the production, structural details, physicochemical properties, and innovative applications of these nanocelluloses. Promising technical applications including gels/foams, thickeners/stabilizers as well as reinforcing agents have been proposed and research from last five years indicates new potential for groundbreaking innovations in the areas of cosmetic products, wound dressings, drug carriers, medical implants, tissue engineering, food and composites. The current state of worldwide commercialization and the challenge of reducing nanocellulose production costs are also discussed.

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Section: Research: Reviewmentioning

confidence: 99%

Nanocellulose as a natural source for groundbreaking applications in materials science: Today’s state

et al. 2018

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“…Another type of modified airlift reactor is a spherical bubble column reactor. This type of reactor has been used by Choi et al to produce BC. They reported a maximum BC concentration of 6.8 g L −1 .…”

Section: Bioreactor Systems For Bc Productionmentioning

confidence: 99%

More Than Meets the Eye in Bacterial Cellulose: Biosynthesis, Bioprocessing, and Applications in Advanced Fiber Composites

et al. 2013

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Bacterial cellulose (BC) nanofibers are one of the stiffest organic materials produced by nature. It consists of pure cellulose without the impurities that are commonly found in plant-based cellulose. This review discusses the metabolic pathways of cellulose-producing bacteria and the genetic pathways of Acetobacter xylinum. The fermentative production of BC and the bioprocess parameters for the cultivation of bacteria are also discussed. The influence of the composition of the culture medium, pH, temperature, and oxygen content on the morphology and yield of BC are reviewed. In addition, the progress made to date on the genetic modification of bacteria to increase the yield of BC and the large-scale production of BC using various bioreactors, namely static and agitated cultures, stirred tank, airlift, aerosol, rotary, and membrane reactors, is reviewed. The challenges in commercial scale production of BC are thoroughly discussed and the efficiency of various bioreactors is compared. In terms of the application of BC, particular emphasis is placed on the utilization of BC in advanced fiber composites to manufacture the next generation truly green, sustainable and renewable hierarchical composites.

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“…Although there were some attempts to scale‐up submerged production of BNC, almost all reports concern air‐lift reactors or bubble‐column reactors (derived from the air‐lift reactor) . That work was mainly focused on oxygen transfer rate, modelling of the process, and on other cultivation‐related factors.…”

Section: Introductionmentioning

confidence: 99%

Scale‐up of production of bacterial nanocellulose using submerged cultivation

Chen

Alriksson³

et al. 2018

J of Chemical Tech & Biotech

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BACKGROUND: More extensive utilization of bacterial nanocellulose (BNC) is severely restricted by the low efficiency and small scale of the traditional static cultivation. Submerged fermentation in stirred-tank reactors (STRs) is potentially favourable for large-scale production of BNC, but scale-up of cultivation remains challenging. Even though the STR is most commonly used for submerged cultivation in the fermentation industry, there are few previous attempts to scale-up production of BNC to pilot scale using an STR. Furthermore, the question of how scale-up of submerged cultivation affects the properties of the BNC has received very little attention RESULTS: Four strains were compared in 250-mL shake flasks. Strain DHU-ATCC-1 displayed the highest volumetric productivity, 0.56 g L −1 d −1 , and was then cultivated in a 400-mL STR, showing a similar productivity of 0.55 g L −1 d −1 . Scale-up using a 75-L STR pilot bioreactor resulted in enhancement of the BNC production rate from 0.056 g d −1 in the shake flasks to 17.3 g d −1 in the 75-L STR, although the productivity decreased to 0.43 g L −1 d −1 . During scale-up from shake flasks to 400-mL STR and further on to 75-L STR, the BNC fibers formed more bundles, whereas the fiber diameter decreased from 25.6 to 21.7 nm. The BNC from the 75-L STR exhibited a higher degree of polymerization, specifically 3230, higher degree of crystallinity, specifically 83%, larger crystallites, and improved strength including higher tensile energy absorption index and superior stretch at break. CONCLUSION: It is possible to enhance BNC production, and maintain or improve its properties when scaling up submerged cultivation in STRs. Washing and weighing of BNC for determining productivity and yieldAfter collection by centrifugation, the crude BNC product was washed with deionized water. The volume of deionized water was half that of the sample volume. After fierce stirring, the crude BNC

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Properties of bacterial cellulose produced in a pilot-scale spherical type bubble column bioreactor

Cited by 34 publications

References 13 publications

Nanocellulose as a natural source for groundbreaking applications in materials science: Today’s state

Nanocellulose as a natural source for groundbreaking applications in materials science: Today’s state

More Than Meets the Eye in Bacterial Cellulose: Biosynthesis, Bioprocessing, and Applications in Advanced Fiber Composites

Scale‐up of production of bacterial nanocellulose using submerged cultivation

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