Properties of a New Chloramine Disinfectant and Detoxicant

Mora, E. C.; Kohl, Herbert H.; Wheatley, W. B.; Worley, S. D.; Faison, J. H.; Burkett, H. D.; Bodor, Nicholas

doi:10.3382/ps.0611968

Cited by 22 publications

(11 citation statements)

References 10 publications

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“…In a possibly more statistically meaningful study, compound I was fed to over 100 broiler chicks for 8 weeks in their drinking water at a concentration of 200 mg/€. 105 Microscopic and macroscopic tissue evaluation at the end of the study revealed no abnormalities relative to control groups. The groups drinking water containing compound I weighed about 5% more on the average than those in the control groups.…”

Section: <1mentioning

confidence: 99%

Halamine water disinfectants

Worley

Williams

Crawford

1988

Critical Reviews in Environmental Control

184

199

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Section: <1mentioning

confidence: 99%

Halamine water disinfectants

Worley

Williams

Crawford

1988

Critical Reviews in Environmental Control

184

199

View full text Add to dashboard Cite

“…The antimicrobial activities and mechanisms of these agents differ considerably. Among them, organic N-halamines have been demonstrated to be a class of effective, durable and reachargeable antimicrobial agents with low toxicity and little environmental concern [31][32][33][34][35][36][37][38].…”

Section: Introductionmentioning

confidence: 99%

Biocidal efficacy, biofilm-controlling function, and controlled release effect of chloromelamine-based bioresponsive fibrous materials

2007

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In this study, 2-amino-4-chloro-6-hydroxy-s-triazine (ACHT) was synthesized through controlled hydrolysis of 2-amino-4,6-dichloro-s-triazine (ADCT). A simple paddry-cure approach was employed to immobilize ACHT onto cellulosic fibrous materials. After treatment with diluted chlorine bleach, the covalently bound ACHT moieties were transformed into chloromelamines. The structures of the samples were fully characterized with NMR, UV/VIS, DSC, TG, iodometric titration and elemental analyses. The chloromelamine-based fibrous materials provided potent, durable, and rechargeable biocidal functions against bacteria (including multi-drug resistant species), yeasts, viruses, and bacterial spores. SEM studies demonstrated that the new fibrous materials could effectively prevent the formation of biofilms, and controlled release investigations in vitro suggested that the biocidal activities were bioresponsive. Biocidal mechanisms of the chloromelamine-based fibrous materials were further discussed.

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“…None of the N-halamine compounds in the present study have been yet approved for direct food contact. However, early results concerning ingestion of Compound I by chickens were certainly encouraging in this regard (Mora et al, 1982).…”

Section: Resultsmentioning

confidence: 97%

Research Note: Combined Halogen Disinfectants in Poultry Processing

1990

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Three organic N-halamine compounds (combined halogen disinfectants) were compared with free chlorine (as calcium hypochlorite) as bactericides against Salmonella typhimurium and unidentified normal poultry bacterial flora under controlled conditions of pH, temperature, and halogen demand similar to those encountered in poultry processing. Two of the compounds (3-chloro-4,4-dimethyl-2-oxazolidinone and 1,3-dichloro-4,4,5,5-tetramethyl-2-imidazolidinone) at a concentration of 50 mg/L were found to cause a 99.9999% decline in viable organisms in less than 1 min at 48 C, whereas a third compound (1-bromo-3-chloro-4,4,5,5-tetramethyl-2-imidazolidinone) was found to be less suitable (5.6 min to 99.9999% decline under the same conditions).

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Properties of a New Chloramine Disinfectant and Detoxicant

Cited by 22 publications

References 10 publications

Halamine water disinfectants

Halamine water disinfectants

Biocidal efficacy, biofilm-controlling function, and controlled release effect of chloromelamine-based bioresponsive fibrous materials

Research Note: Combined Halogen Disinfectants in Poultry Processing

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