Propagation of deep venous thrombosis identified by duplex ultrasonography

Krupski, William C.; Bass, Arie; Dilley, Ralph B.; Bernstein, Eugene F.; Otis, Shirley M.

doi:10.1016/0741-5214(90)90049-g

Cited by 113 publications

(26 citation statements)

References 49 publications

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“…[23][24][25][26][27][28][29] When duplex scanning was used to document recurrent thrombosis in patients receiving heparin therapy for acute DVT, Krupski et al found a 38% recurrence rate within the acute period 30 -a figure that is more in accord with the cumulative incidence of recurrence observed in this study.…”

Section: Discussionsupporting

confidence: 79%

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Venous thrombus stability during acute phase of therapy

et al. 1999

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Abstract:The purpose of this study was to use serial venous duplex scans to document the status of deep venous thrombi during the early phase of therapy for acute, deep-vein thrombosis (DVT). A total of 71 consecutive participants treated for a first episode of acute DVT were monitored for new venous thrombosis using serial venous duplex scans. An average of 4.6 duplex scans were performed per patient (range, three to seven) during the 3-week study period. The cumulative incidence of contiguous/non-contiguous extension of the DVT at 3 weeks was 26% (95% CI = 14% to 38%). Nine of the 15 (60%) occurrences were asymptomatic. None of the classical risk factors for DVT was significantly associated with the development of new thrombi. The fraction of time during which the level of anticoagulation was considered 'adequate' (international normalized ratio у2.0 and/or heparin concentration у0.2 IU/ml) was inversely associated with the risk of extension/new thrombi (p = 0.01, Cox proportional hazards analysis).It was concluded that: (1) the frequency of contiguous/non-contiguous extension of venous thrombosis detectable during the first 3 weeks of therapy was higher than previously reported; (2) the majority of the occurrences were asymptomatic; and (3) the risk of developing this complication was inversely associated with the level of anticoagulation achieved.

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Section: Discussionsupporting

confidence: 79%

“…23,30 Duplex scans were performed with an Ultramark 9 duplex scanner (Advanced Technology Laboratories, Bothell, WA, USA). A 5-MHz linear-array color transducer with a 5-MHz pulsed Doppler flow detector were used to image the infrainguinal veins; a 3.5-MHz phased-array transducer was used to image the iliac veins and the inferior vena cava.…”

Section: Methodsmentioning

confidence: 99%

Venous thrombus stability during acute phase of therapy

et al. 1999

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“…[1][2][3][4][5][8][9][10][11][12][13][14] Like Ramshorst et al, 8 we used a semiquantitative index for both initial and followup scoring of the thrombosis. Ramshorst et al studied 80 thrombosed venous segments, 49 of which involved the popliteal and femoral veins.…”

Section: Discussionmentioning

confidence: 99%

Short- and medium-term duplex sonography follow-up of deep venous thrombosis of the lower limbs

Baud

Stephas

Ribadeau-Dumas

et al. 1998

J. Clin. Ultrasound

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“…22 Patients with extensive DVT treated by anticoagulants usually present fairly poor rates of spontaneous short-time recanalization. [23][24][25] Catheter-directed venous lysis enables the changing of the natural history of venous thrombosis, promoting early removal of the thrombus and re-establishment of venous patency.…”

Section: Discussionmentioning

confidence: 99%