Propagation of Cylindrical Vector Laser Beams in Turbid Tissue-Like Scattering Media

Doronin, Alexander; Vera, Nicolas; Staforelli, Juan Pablo; Coelho, Pablo; Meglinski, Igor

doi:10.3390/photonics6020056

Cited by 24 publications

(18 citation statements)

References 51 publications

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“…In recent years, the connection between attenuation and OAM has been investigated in the context of biology and medicine 7,8,13,[19][20][21] . Studies that have used numerical methods that model this problem have shown that increasing the topological charge does improve permeability and increases the contrast of the outgoing beam [22][23][24] . These results were consistent with results of other experiments on OAM transmission 22 .…”

mentioning

confidence: 99%

“…Studies that have used numerical methods that model this problem have shown that increasing the topological charge does improve permeability and increases the contrast of the outgoing beam [22][23][24] . These results were consistent with results of other experiments on OAM transmission 22 . In this work, we use relatively thicker biological tissue, reaching the cm range.…”

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confidence: 99%

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OAM light propagation through tissue

Biton

Kupferman

Arnon

2021

Sci Rep

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A major challenge in use of the optical spectrum for communication and imaging applications is the scattering of light as it passes through diffuse media. Recent studies indicate that light beams with orbital angular momentum (OAM) can penetrate deeper through diffuse media than simple Gaussian beams. To the best knowledge of the authors, in this paper we describe for the first time an experiment examining transmission of OAM beams through biological tissue with thickness of up to a few centimeters, and for OAM modes reaching up to 20. Our results indicate that OAM beams do indeed show a higher transmittance relative to Gaussian beams, and that the greater the OAM, the higher the transmittance also up to 20, Our results extend measured results to highly multi scattering media and indicate that at 2.6 cm tissue thickness for OAM of order 20, we measure nearly 30% more power in comparison to a Gaussian beam. In addition, we develop a mathematical model describing the improved permeability. This work shows that OAM beams can be a valuable contribution to optical wireless communication (OWC) for medical implants, optical biological imaging, as well as recent innovative applications of medical diagnosis.

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confidence: 99%

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confidence: 99%

OAM light propagation through tissue

Biton

Kupferman

Arnon

2021

Sci Rep

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“…The variety of these vectors does depend upon the anisotropy of the medium, giving useful insight towards the detection and grading of cervical precancer. There are some reports that employ the use of complex vector beams for diagnosis purpose. These beams are independent of the anisotropy of the medium and can unify the currently available polarimetry.…”

Section: Resultsmentioning

confidence: 99%

Mapping of retardance, diattenuation and polarizance vector on Poincare sphere for diagnosis and classification of cervical precancer

Zaffar

Pradhan

2020

Journal of Biophotonics

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The mapping of diattenuation, polarizance and retardance vector (normalized Stokes vector) on Poincare sphere, evaluated from Mueller matrix of optically anisotropic stromal region of cervical tissues, is presented for cervical precancer detection and its staging. This reveals that the changes in the polarization states shown by these normalized Stokes vectors corresponds to the degradation of linearly arranged collagen fibers, breakage of the collagen cross links in the stromal region and change in the density of scattering sites when cervical cancer evolves. The distinct nature of real and imaginary parts of the refractive index for linear, linear-45 and circular polarization from the optically anisotropic stromal region underscore the various polarization structures of the connective tissue region which get modified during the pathological changes. It has been found that versatility of these vectors for normal and precancerous cervical tissue of various grades may be utilized as a key distinction for qualitative staging of cervical precancer tissue. Quantitative classification of precancerous stages of cervical precancer has been determined with 95%-100% sensitivity and 93%-100% specificity through the evaluation of linear and circular diattenuation, linear polarizance and linear birefringence from the components of the respective vectors. K E Y W O R D S cervical cancer, diattenuation vector, Mueller matrix, Poincare sphere, polarizance vector, retardance vector, stromal region

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“…In a continuation of previous research, in [66] using Monte-Carlo simulation with GPU CUDA the propagation of cylindrical vector beams (CVB) in turbid tissuelike scattering media was explored in comparison with conventional Gaussian laser beams. The authors also pioneered the application of MC for imitation of the propagation of vector light beams in turbid media.…”

Section: Polarimetry and Mueller Matrix Measurementmentioning

confidence: 99%

Advances in the simulation of light–tissue interactions in biomedical engineering

2019

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Monte Carlo (MC) simulation for light propagation in scattering and absorbing media is the gold standard for studying the interaction of light with biological tissue and has been used for years in a wide variety of cases. The interaction of photons with the medium is simulated based on its optical properties and the original approximation of the scattering phase function. Over the past decade, with the new measurement geometries and recording techniques invented also the corresponding sophisticated methods for the description of the underlying light-tissue interaction taking into account realistic parameters and settings were developed. Applications, such as multiple scattering, optogenetics, optical coherence tomography, Raman spectroscopy, polarimetry and Mueller matrix measurement have emerged and are still constantly improved. Here, we review the advances and recent applications of MC simulation for the active field of the life sciences and the medicine pointing out the new insights enabled by the theoretical concepts.

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Propagation of Cylindrical Vector Laser Beams in Turbid Tissue-Like Scattering Media

Cited by 24 publications

References 51 publications

OAM light propagation through tissue

OAM light propagation through tissue

Mapping of retardance, diattenuation and polarizance vector on Poincare sphere for diagnosis and classification of cervical precancer

Advances in the simulation of light–tissue interactions in biomedical engineering

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