Promoting Early Child Development With Interventions in Health and Nutrition: A Systematic Review

Vaivada, Tyler; Gaffey, Michelle F; Bhutta, Zulfiqar A

doi:10.1542/peds.2016-4308

Cited by 77 publications

(67 citation statements)

References 111 publications

(111 reference statements)

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“…The ages of attainment of play milestones in healthy children across countries is of utmost importance to integrated interventions that include play and are being highly promoted in LMICs. 3,27 A large proportion of the differences in ages of attainment of milestones was associated with timing of children's exposure to experiences. For example, South African children could drink from a cup at a median age of 8 months compared with Argentinian children who reached this milestone at a median age of 16 months.…”

Section: Discussionmentioning

confidence: 99%

Similarities and differences in child development from birth to age 3 years by sex and across four countries: a cross-sectional, observational study

Ertem

Krishnamurthy²,

Mulaudzi

et al. 2018

The Lancet Global Health

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Section: Discussionmentioning

confidence: 99%

Similarities and differences in child development from birth to age 3 years by sex and across four countries: a cross-sectional, observational study

Ertem

Krishnamurthy²,

Mulaudzi

et al. 2018

The Lancet Global Health

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“…54,55 Research into neuroprotective interventions early in life leads to more clear conclusions: antenatal corticosteroids to prevent developmental delays and antenatal magnesium sulfate to prevent gross motor dysfunction showed significant effect sizes of 0.49 (95% confidence interval 0.24 to 1.00) and 0.61, respectively (95% confidence interval 0.44 to 0.85). 56 In addition, the generally improved neonatal intensive care has resulted in a decrease in the prevalence of cerebral palsy, 57 which is strongly related to CVI. 39,40…”

Section: Visuospatial Consequences Of Very Preterm Birthmentioning

confidence: 99%

Brain Damage and Visuospatial Impairments: Exploring Early Structure-Function Associations in Children Born Very Preterm

Gils¹,

Dudink

Swarte

et al. 2020

Pediatric Neurology

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Background: To provide insight into early neurosensory development in children born very preterm, we assessed the association between early structural brain damage and functional visuospatial attention and motion processing from one to two years corrected age. Methods: In 112 children born at less than 32 weeks gestational age, we assessed brain damage and growth with a standardized scoring system on magnetic resonance imaging (MRI; 1.5 Tesla) scans performed at 29 to 35 weeks gestational age. Of the children with an MRI scan, 82 participated in an eye tracking-based assessment of visuospatial attention and motion processing (Tobii T60XL) at one year corrected age and 59 at two years corrected age. Results: MRI scoring showed good intra-and inter-rater reproducibility. At one year, 10% children had delayed attentional reaction times and 23% had delayed motion reaction times. Moderate to severe brain damage significantly correlated with slower visuospatial reaction times. At two years, despite attention and motion reaction times becoming significantly faster, 20% had delayed attentional reaction times and 35% had delayed motion reaction times, but no correlations with MRI scores were found. The presence of structural brain damage was associated with abnormal functional performance over age. Conclusions: The present study indicates an association between moderate to severe brain damage and visuospatial attention and motion processing dysfunction at one year corrected age. This provides a new perspective on comprehensive MRI scoring and quantitative functional visuospatial assessments and their applicability in children born very preterm in their first years of life.

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“…In high‐income countries, early identification of children with developmental difficulties is an integral component of child health care and children who are identified receive individualised, family‐centred and comprehensive early interventions . In contrast, child development is rarely addressed during health care in low‐income and middle‐income countries, and nonindividualised interventions involve promoting nurturing care . While these universal strategies are crucial, complementary individualised approaches are also urgently needed to help close the unethical equity gap for children around the world .…”

Section: Introductionmentioning

confidence: 99%

Validation of the International Guide for Monitoring Child Development demonstrates good sensitivity and specificity in four diverse countries

Ertem

Krishnamurthy²,

Mulaudzi

et al. 2018

Acta Paediatrica

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Aim: It is of critical importance to have internationally constructed tools to address early childhood development. The aim of this second phase of a two-phase study was to examine the sensitivity and specificity of the Guide for Monitoring Child Development (GMCD) in identifying developmental delay in four diverse countries.Methods: The first phase of this 2011-2015 back-to-back study included 4949 children up to 42 months of age from primary healthcare centres in Argentina, India, South Africa and Turkey. Distribution curves were generated to show the ages when the children attained GMCD milestones and those that could be used across sexes and countries were placed in age ranges corresponding to the 85th and 97th percentile point estimates. Phase two examined a separately recruited sample of children in those countries to determine sensitivity and specificity of the GMCD. Results:The validation phase of the 85 milestones in the GMCD identified delayed development in 30% of the 1731 children in the four countries. The sensitivity and specificity ranged from 0.71-0.94 and 0.69-0.82, respectively, for the total sample and the different age groups.

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Promoting Early Child Development With Interventions in Health and Nutrition: A Systematic Review

Abstract: These findings should guide the prioritization and scale-up of interventions within critical periods of early infancy and childhood, and encourage research into their implementation at scale.

Cited by 77 publications

References 111 publications

Similarities and differences in child development from birth to age 3 years by sex and across four countries: a cross-sectional, observational study

Similarities and differences in child development from birth to age 3 years by sex and across four countries: a cross-sectional, observational study

Brain Damage and Visuospatial Impairments: Exploring Early Structure-Function Associations in Children Born Very Preterm

Validation of the International Guide for Monitoring Child Development demonstrates good sensitivity and specificity in four diverse countries

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