Promoting Cardiovascular Health in Early Childhood and Transitions in Childhood through Adolescence: A Workshop Report

Daniels, Stephen R.; Pratt, Charlotte; Hollister, Emily B.; Labarthe, Darwin R.; Cohen, Deborah A.; Walker, Jenelle; Beech, Bettina M.; Balagopal, Prabhakaran; Beebe, Dean W.; Gillman, Matthew W.; Goodrich, Jaclyn M.; Jaquish, Cashell E.; Kit, Brian K.; Miller, Alison L.; Olds, David L.; Oken, Emily; Rajakumar, Kumaravel; Sherwood, Nancy E.; Spruijt‐Metz, Donna; Steinberger, Julia; Suglia, Shakira F.; Teitelbaum, Susan L.; Urbina, Elaine M.; Horn, Linda Van; Ward, Dianne S.; Young, Martin E.

doi:10.1016/j.jpeds.2019.01.042

Cited by 28 publications

(14 citation statements)

References 107 publications

(108 reference statements)

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“…However, this risk can be reversed if individuals attain a low level of adiposity by adolescence or avoid becoming obese. Identifying children at high risk of developing obesity would allow preventive and intervention efforts to be initiated at an early life-stage ( 101 , 102 ).…”

Section: Early Prediction Of Future Cardiometabolic Riskmentioning

confidence: 99%

Childhood obesity: rapid weight gain in early childhood and subsequent cardiometabolic risk

Arisaka

Ichikawa

Koyama

et al. 2020

Clin Pediatr Endocrinol

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. Dynamic changes in body weight have long been recognized as important indicators of risk for human health. Many population-based observational studies have shown that rapid weight gain during infancy, including a catch-up growth phenomenon or adiposity rebound in early childhood, predisposes a person to the development of obesity, type 2 diabetes, and cardiovascular diseases later in life. However, a consensus has not been established regarding which period of weight gain contributes to future risks. This review evaluates recent evidence on the relationship between early rapid growth and future obesity and cardiometabolic risk, with a focus on the differential significance of rapid weight gain in infancy and early childhood. Although there is a need for attention to childhood growth during early infancy before 1 yr of age as it may be related to future obesity, emerging evidence strongly suggests that toddlers showing an increase in body mass index (BMI) before 3 yr of age, a period normally characterized by decreased BMI, are prone to developing later cardiometabolic risk.

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Section: Early Prediction Of Future Cardiometabolic Riskmentioning

confidence: 99%

Childhood obesity: rapid weight gain in early childhood and subsequent cardiometabolic risk

Arisaka

Ichikawa

Koyama

et al. 2020

Clin Pediatr Endocrinol

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“…This study demonstrated the typical trajectory curves of RV function and established reference values of the TAPSE Numerous studies have shown that cardiovascular disease (CVD) that ultimately results in disability and premature death outcomes begins in childhood and progresses into adulthood [1][2][3][4][5]. Among childhood CVD risk factors, BMI is the strongest predictor of adult metabolic syndrome [6], defined as a cluster of abnormalities, including central obesity, increased blood pressure, lipid abnormalities, and impaired glucose tolerance, all are well-documented risk factors for CVD.…”

mentioning

confidence: 60%

Focusing on cardiovascular health in early life: the application of echocardiography

Guo

2022

Int J Cardiovasc Imaging

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“…1 This allows us to draw attention to our reported cohort of 38 children with a liver disease of indeterminate etiology, in most cases presenting with acute hepatitis (n = 14) or with PALF (n = 15). 2 This condition was tentatively called "seronegative autoimmune hepatitis" because of the liver histology, the prompt response to immunosuppressive therapy used in typical autoimmune hepatitis 3,4 (prednisone alone or with azathioprine or cyclosporine), and the lack of specific autoantibodies. These features, combined with the lack of evidence of known causes of acute and chronic liver diseases, suggested immune dysregulation and activation.…”

Section: Immunosuppressive Therapy For Indeterminate Acute Hepatitis mentioning

confidence: 99%

Early increase in body mass index and cardiometabolic risk in adolescence

Arisaka

Ichikawa

Koyama

et al. 2019

The Journal of Pediatrics

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Early increase in body mass index and cardiometabolic risk in adolescence To the Editor: In an assessment of the influence of the weight gain trajectory from birth to 14 years old, Barraclough et al found that an early increase in body mass index (BMI) above the 90th percentile before 3 years of age resulted in an unfavorable cardiometabolic risk profile in adolescence, compared with children with a late increase in BMI. 1 This finding is important because early identification of children with likely future cardiometabolic risks is essential for promoting cardiovascular health in early childhood. 2 We would like to add our view on the relationship between the early BMI pattern and cardiometabolic risk. Early excess BMI before 3 years of age is important in relation to future cardiometabolic risk, but it is not necessary for the child to be overweight or obese at the start of the BMI rise. 1,3 We have found that a BMI increase from age 1.5 to 3.0 years, even if BMI is in the normal range just before the increase, is related to a greater increase in Homeostatic Model Assessment of Insulin Resistance per BMI increase at age 12 years compared with a stable or decreased BMI from 1.5 to 3.0 years of age. 4-6 These data were obtained from 1.5-and 3.0-year-old checkups, including weight and height measurements, as defined by the Ministry of Health, Labour and Welfare in Japan. This finding suggests that children with a BMI increase before age 3 years, a period normally characterized by decreased BMI, are more prone to developing insulin resistance in adolescence. Furthermore, another analysis of longitudinal growth data indicated that BMI rebound (adiposity rebound) earlier than approximately 3 years of age with lower pre-rebound BMI leads to greater risk of childhood obesity. 7 These results suggest that an early increase in BMI before age 3 years is important, even if the absolute BMI is low, because this BMI pattern is closely related to cardiometabolic risk in adolescence.

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Promoting Cardiovascular Health in Early Childhood and Transitions in Childhood through Adolescence: A Workshop Report

Cited by 28 publications

References 107 publications

Childhood obesity: rapid weight gain in early childhood and subsequent cardiometabolic risk

Childhood obesity: rapid weight gain in early childhood and subsequent cardiometabolic risk

Focusing on cardiovascular health in early life: the application of echocardiography

Early increase in body mass index and cardiometabolic risk in adolescence

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