Promoting analysis of real-world data: Prospects for preventive cardiology in Japan

Abstract

CVD and cerebrovascular disease account for 23.2% of all deaths (2).According to the United States statistics for 2018, the leading causes of the 2,813,503 deaths per year in the United States are heart disease (647,457), malignant neoplasms (599,108), accidents (169,936), chronic respiratory diseases (160,201), and strokes (146,383). CVD account for 28.2% of all deaths, including heart disease and stroke (3). Conquering CVD is a challenge not only for Japan, but for most developed countries.The place of CVD in the history of medicine has largely changed. Today, the novel coronavirus infection (COVID-19) is rampant throughout the world. Since the dawn of history, infectious diseases have been the greatest threat to humanity. The Black Death in the 14 th and 16 th centuries and the Spanish flu in the early 20 th century are the most notable examples of infectious disease pandemics. In Japan, tuberculosis was the leading cause of death in the early 20th century (the death rate from tuberculosis in 1918 was 257.1 per 100,000 people, far higher than that of malignant neoplasms ( 4)). On the (P1)