Promising Male Hormonal Contraceptive are Well Established Soon a Reality

Abstract

Objective: To understand the modalities used for male hormonal
 contraception.
 Methods: Literature review
 Conclusion: Male contraceptive methods are still limited but hormonal
 contraceptive methods are being developed. The basic
 mechanism of male hormonal contraception is to inhibit spermatogenesis
 by suppression of the hypothalamic-pituitary-testicular axis
 function. Administration of testosterone or androgen derivative that
 is given in combination with progestin or GnRH antagonist shows
 that male hormonal contraceptive is reversible, effective, and acceptable
 as a male contraceptive method. However, no method of male
 hormonal contraceptive is ready for clinical use and marketed due
 to limited studies.
 [Indones J Obstet Gynecol 2015; 3-4: 239-243]
 Keywords: GnRH antagonist, male hormonal contraceptive, progestin,
 testosterone