Promising bioactivities of postbiotics: A comprehensive review

Rafique, Nazrana; Jan, S.; Dar, Aamir Hussain; Dash, Kshirod Kumar; Sarkar, Anwesa; Shams, Rafeeya; Pandey, Vinay Kumar; Khan, Shafat Ahmad; Amin, Quraazah Akeemu; Hussain, Syed Zameer

doi:10.1016/j.jafr.2023.100708

Cited by 26 publications

(9 citation statements)

References 165 publications

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“…These metabolites play a crucial role in regulating bacterial growth and cell communication. Additionally, they contribute to the growth of beneficial bacteria and offer protection against various stresses [ 64 ].…”

Section: Resultsmentioning

confidence: 99%

Assessment of the Physicochemical, Antioxidant, Microbial, and Sensory Attributes of Yogurt-Style Products Enriched with Probiotic-Fermented Aronia melanocarpa Berry Juice

Plessas,

Mantzourani,

Terpou

et al. 2023

Foods

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The aim(目的) of this study was to create(创建) various formulations of yogurt enriched with freeze(冻结)-dried adjuncts, namely(即) (i) probiotic Lactobacillus plantarum ATCC 14917 culture(文化), and (ii) L. plantarum ATCC 14917 fermented black chokeberry juice, along with a commercial(商业) starter culture(文化). The goal was to enhance(提高) functionality and optimize the nutritional(营养) value(价值) of the products. These new yogurt-style(风格) formulations were subsequently(随后) compared with commercially produced yogurt. All products demonstrated(演示) favorable(有利) physicochemical properties, and the probiotic strain(应变) consistently(一贯) maintained viable(可行) levels exceeding 7 log(日志) cfu/g throughout(遍及) the entire(整个) storage(存储) period(时期). The fermented milk produced with the adjunct-free L. plantarum cells, as well as the yogurt produced with the proposed(提出) lactobacilli-fermented chokeberry juice, exhibited the highest lactic acid(酸) production(生产) (1.44 g/100 g yogurt by the end of storage(存储)). Levels of syneresis were observed at lower(较低) values(价值) in yogurt produced with freeze(冻结)-dried fermented chokeberry juice. Yogurts prepared(准备) with the lactobacilli-fermented freeze(冻结)-dried chokeberry juice displayed elevated total(总) phenolic content(内容) and antioxidant capacity(容量) (25.74 µg GAE/g and 69.05 µmol TE/100 g, respectively(分别)). Furthermore, sensory tests revealed a distinctive(鲜明) fruity flavor(风味) in samples incorporating fermented juice. The results demonstrate(演示) that probiotic L. plantarum-fermented chokeberry juice enhances(提高) both the antioxidant capacity(容量) and the viability of beneficial(有益) bacteria(细菌) in yogurt while it can be readily(欣然) applied and commercialized, especially in the form of a freeze(冻结)-dried formulation.

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Section: Resultsmentioning

confidence: 99%

Assessment of the Physicochemical, Antioxidant, Microbial, and Sensory Attributes of Yogurt-Style Products Enriched with Probiotic-Fermented Aronia melanocarpa Berry Juice

Plessas,

Mantzourani,

Terpou

et al. 2023

Foods

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“…Postbiotics have been linked to several additional and recently discovered health advantages like allergy control and others. According to research on individuals with eczema, the severity of the illness was greatly lessened by taking a postbiotic supplement for 8–12 weeks [ 208 , 210 ]. Furthermore, these probiotics suppress hunger signals and lead to weight loss; they play an important role in reducing the risk of cardiovascular diseases and have anti-tumor activities as they inhibit the growth and spread of the cancerous cells [ 211 ].…”

Section: Probiotics/symbiotics/postbioticsmentioning

confidence: 99%

The Networked Interaction between Probiotics and Intestine in Health and Disease: A Promising Success Story

Skoufou,

Tsigalou,

Vradelis

et al. 2024

Microorganisms

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Probiotics are known to promote human health either precautionary in healthy individuals or therapeutically in patients suffering from certain ailments. Although this knowledge was empirical in past tomes, modern science has already verified it and expanded it to new limits. These microorganisms can be found in nature in various foods such as dairy products or in supplements formulated for clinical or preventive use. The current review examines the different mechanisms of action of the probiotic strains and how they interact with the organism of the host. Emphasis is put on the clinical therapeutic use of these beneficial microorganisms in various clinical conditions of the human gastrointestinal tract. Diseases of the gastrointestinal tract and particularly any malfunction and inflammation of the intestines seriously compromise the health of the whole organism. The interaction between the probiotic strains and the host’s microbiota can alleviate the clinical signs and symptoms while in some cases, in due course, it can intervene in the underlying pathology. Various safety issues of the use of probiotics are also discussed.

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“…Most of the currently existing postbiotics are derived from bacteria of the Lactobacillus or Bifidobacterium bacterial genera, but also from yeasts such as Saccharomyces cerevisiae, mainly from the fermentation of these bacteria carried out in industrial processes [100][101][102][103][104][105] . Postbiotics are commonly metabolites or polysaccharides, substances with antioxidants, anti-inflammatory or even immunomodulatory properties [15,95,100] .…”

Section: Postbioticsmentioning

confidence: 99%

Past, present, and future of microbiome-based therapies

Manrique,

Montero,

Fernandez-Gosende

et al. 2024

Microbiome Res Rep

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Technological advances in studying the human microbiome in depth have enabled the identification of microbial signatures associated with health and disease. This confirms the crucial role of microbiota in maintaining homeostasis and the host health status. Nowadays, there are several ways to modulate the microbiota composition to effectively improve host health; therefore, the development of therapeutic treatments based on the gut microbiota is experiencing rapid growth. In this review, we summarize the influence of the gut microbiota on the development of infectious disease and cancer, which are two of the main targets of microbiome-based therapies currently being developed. We analyze the two-way interaction between the gut microbiota and traditional drugs in order to emphasize the influence of gut microbial composition on drug effectivity and treatment response. We explore the different strategies currently available for modulating this ecosystem to our benefit, ranging from 1st generation intervention strategies to more complex 2nd generation microbiome-based therapies and their regulatory framework. Lastly, we finish with a quick overview of what we believe is the future of these strategies, that is 3rd generation microbiome-based therapies developed with the use of artificial intelligence (AI) algorithms.

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Promising bioactivities of postbiotics: A comprehensive review

Cited by 26 publications

References 165 publications

Assessment of the Physicochemical, Antioxidant, Microbial, and Sensory Attributes of Yogurt-Style Products Enriched with Probiotic-Fermented Aronia melanocarpa Berry Juice

Assessment of the Physicochemical, Antioxidant, Microbial, and Sensory Attributes of Yogurt-Style Products Enriched with Probiotic-Fermented Aronia melanocarpa Berry Juice

The Networked Interaction between Probiotics and Intestine in Health and Disease: A Promising Success Story

Past, present, and future of microbiome-based therapies

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