Promising antifungal effect of some Euro-Asiatic plants against dangerous pathogenic and toxinogenic fungi

Abstract

This study has identified 14 extracts of medicinal plants with a potential use as an antifungal treatment in various areas. One of them showed promising efficiency against all selected significant pathogenic and toxinogenic fungal species.

Gene Discovery of Modular Diterpene Metabolism in Nonmodel Systems

“…1). We included several species that are being explored, or are already being used, for development or production of diterpene pharmaceuticals: marrubiin 7 produced in Marrubium vulgare (Lamiaceae; Meyre-Silva and Cechinel-Filho, 2010), forskolin 8 produced in Coleus forskohlii (Lamiaceae; Melzig, 2010a, 2010b), grindelic acid 9 produced in Grindelia robusta (Asteraceae; Zabka et al, 2011), triptolide 4 produced in Tripterygium wilfordii (Celastraceae; Brinker et al, 2007), oridonin 5 produced in Isodon rubescens (Lamiaceae; Li et al, 2011), pseudolaric acid 2 produced in Pseudolarix amabilis (Pinaceae; Chiu et al, 2010), ingenol-3-angelate 10 produced in Euphorbia peplus (Euphorbiaceae) (Li et al, 2010), carnosol 6 produced in Rosmarinus officinalis (Lamiaceae; López-Jiménez et al, 2011), and jatrophone 11 produced in Jatropha gossypiifolia (Euphorbiaceae; Theoduloz et al, 2009). In addition, cis-abienol 3 produced in A. balsamea (Pinaceae) can be used for production of ambroxide fragrances for high-end perfume manufacture (Zerbe et al, 2012a).…”

In Vitro Multiplication of Aromatic and Medicinal Plants and Fungicide Activity

“…Inhalation of conidia by immunocompetent individuals rarely has any adverse effect (Latgé, 1999). However, apart from the production of mycotoxins, A. fumigatus is a dangerous human pathogenic, which is able to cause very serious human and animal mycoses with a high frequency of resistance to chemical antifungal drugs (Verweij et al, 2009;Lass-Florl et al, 2010;Xu et al, 2010;Zabka et al, 2011). Dramatic increases in the incidence of aspergillosis caused primarily by A. fumigatus have occurred in recent years.…”

“…In other way, pathogenic and toxinogenic fungi are one of the major economic problems of crop and food production (Zabka et al, 2011). In terms of food safety, species of Fusarium, Aspergillus and Penicillium genera are considered the most significant because they produce the great majority of known mycotoxins (Palumbo et al, 2008;Zabka et al, 2011).…”

“…In terms of food safety, species of Fusarium, Aspergillus and Penicillium genera are considered the most significant because they produce the great majority of known mycotoxins (Palumbo et al, 2008;Zabka et al, 2011). There has been increasing concern of the consumers about foods free or with lower level of chemical preservatives because these could be toxic for humans (Bedin et al, 1999;Souza et al, 2005).…”

“…The most important of these bioactive compounds of plants are alkaloids, flavanoids, tannins and phenolic compounds (Edeoga et al, 2005;Panghal et al, 2011). Some medicinal plants exert strong antifungal properties and could be conveniently used as a promising alternative source for presently problematic antifungal treatment in many areas with respect to their natural origin (Zabka et al, 2011).…”