Prolotherapy: A new hope for temporomandibular joint pain

Kumar, Ashish; Jaishankar, H. P.; Abraham, Kavitha; Naik, Purnachandra Rao

doi:10.4103/0970-5333.119324

Cited by 7 publications

(10 citation statements)

References 4 publications

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“…Temporomandibular Joint Disorders (TMDs) are considered one of the most common causes of pain in the orofacial area. 1 It's a collective term used to describe a group of signs and symptoms affecting the temporomandibular joint (TMJ), masticatory muscles and the associated structures. These disorders can affect the quality life of the patient.…”

Section: Introductionmentioning

confidence: 99%

“…This could be due to the complex nature of this joint, in addition to the lack of complete understanding of the etiology and pathogenesis of this disorder. 1 In the literature, there is a wide variety of treatment modalities of TMDs, including pharmacological, non-surgical and surgical interventions. The main target is to relieve patient's pain in addition to restoring the normal joint function.…”

Section: Introductionmentioning

confidence: 99%

“…[3][4][5][6] Usually the first treatment option used is the performing of jaw exercises by a physiotherapist. 1 If there is no improvement in this kind of treatment, then medical treatment should be initiated. The medications that are most commonly used in the management of TMDs include nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, anti-depressants and antianxiety drugs and muscle relaxants, Also, oral appliances have gained more popularity in the management of TMDs, with various types of occlusal splints.…”

Section: Introductionmentioning

confidence: 99%

“…[7][8][9][10][11] surgical treatment is usually the last resort in the management of TMD, so it is common to look for other alternative treatments. 1 One of treatments is the Low Level Laser Therapy (LLLT) which is one of the recently used treatment modalities in the physiotherapy field. It is also well known as soft laser therapy.…”

Section: Introductionmentioning

confidence: 99%

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Dextrose Prolotherapy versus Low Level Laser Therapy (LLLT) for Management of Temporomandibular Joint Disorders (TMD): Clinical Randomized controlled Study

Hassanien

Kamel

Rashed

2020

Egyptian Dental Journal

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Objective: To compare the effects of dextrose prolotherapy and low level laser therapy in terms of the pain (VAS) and maximum interincisal opening (MIO) in treatment of temporomandibular disorders. Patients and Methods:Twenty patients (10 males & 10 females) with temporomandibular disorders TMD participated in this clinical trial. All patients were randomly divided into two equal groups. In dextrose group; 12.5% Dextrose was injected into 3 targeted areas, the posterior joint space, the anterior disc attachment and superior attachment of masseter muscle. Dextrose prolotherapy was performed at 2 weeks, and 4 weeks intervals. In laser group; semi conductive (diode) gallium arsenide (Ga As) laser was utilized in this study. The therapeutic LLLT application was performed 3 times per week for four consecutive weeks. The primary outcome measure was the severity of the pain at rest assessed with visual analogue scale (0-10 cm). The secondary outcome measure was Maximum interincisal opening (MIO). All the evaluations in both groups were done at baseline, 2 weeks, and 4 weeks subsequent to the treatment.Results :The results demonstrated insignificant difference between the means of dextrose prolotherapy and laser groups in terms of VAS (at rest), MIO degree values before treatment (base line) (p>0.05). When the changes in the groups after treatment were compared, there was no significant difference between the means of dextrose and laser groups regarding VAS (at rest) after 2 weeks and 4 weeks (p-value>0.05). However, there was a statistical significant difference (P-value = 0.001) between the means of both groups regarding MIO after 2 weeks and 4 weeks (P-value <0.001). The improvement in maximum interincisal opening was greater in the group that submit to dextrose prolotherapy in comparison to the laser group (p<0.05). Conclusions:In temporomandibular disorders dextrose prolotherapy is more efficient in improving maximum interincisal opening in comparison to low level laser therapy. However, both treatments have the same effect in reducing pain at rest. KEY WORDS:Temporomandibular disorders, Low level laser therapy, Dextrose prolotherapy (96) Nermeen Hassanien, et al.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Dextrose Prolotherapy versus Low Level Laser Therapy (LLLT) for Management of Temporomandibular Joint Disorders (TMD): Clinical Randomized controlled Study

Hassanien

Kamel

Rashed

2020

Egyptian Dental Journal

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“…It is also known as "sclerotheraphy", "proliferative injection therapy", "regenerative injection therapy" or "ligament sclerotherapy". Autologous blood and ethanolamine oleate are used as proliferant solutions (l6, 17).…”

Section: Introductionmentioning

confidence: 99%

Comparative Study Between 2 Types of Prolotherapy in Treatment of Chronic Recurrent Temporomandibular Joint Dislocation

Khamis

Osman

Mohamed

2019

Alexandria Dental Journal

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INTRODUCTION:Temporomandibular Joint (TMJ) dislocation when condyles travel anterior to articular eminence. It may be reducible or irreducible. Chronic recurrent TMJ dislocation was treated by surgical and nonsurgical methods. Minimally invasive methods include injection of sclerosing agents intra-articular and extra-capsular or botulinum toxin to the surrounding muscles. Prolotherapy is a method of strengthening lax ligaments by injecting various types of sclerosing or proliferant solutions such as ethanolamine oleate 5%, autologus blood and others. It is also known as "ligament sclerotherapy" or "regenerative injection therapy" OBJECTIVES: the study aimed to compare 2 types of prolotherapy (autologous blood & ethanolamine Oleate sclerosing agent) injection in treatment of chronic recurrent temporomandibular joint dislocation. . Thirty patients with chronic recurrent temporomandibular joint dislocation were chosen with certain inclusion and exclusion criteria. Fifteen participants were injected with ethanolamine oleate compared with fifteen patients were injected with autologous blood and were followed-up for six months. The participated patients were assessed at the pre-and post-treatment stages by evaluating pain and mandibular range of motion clinically and radiographically using Magnatic Resonance Imaging (MRI) to evaluate condyle-articular eminence relation in opening and closing mouth. RESULTS: There was no significant difference between both prolotherapies in treating chronic recurrent temporomandibular joint dislocation. CONCLUSIONS: Ethanolamine oleate and autologus blood injection are simple, safe and cost-effective treatment for management of chronic recurrent temporomandibular joint dislocation.

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Ultrasound‐Guided Vs Non‐Guided Prolotherapy for Internal Derangement of Temporomandibular Joint. A Randomized Clinical Trial

Alhaj Kheder,

Kandil,

El‐Ghareeb

et al. 2024

J of Ultrasound Medicine

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ObjectivesThis randomized clinical trial study aims to compare ultrasound‐guided versus non‐guided Dextrose 10% injections in patients suffering from internal derangement in the temporomandibular joint (TMJ).Material and MethodsThe study population included 22 patients and 43 TMJs suffering from unilateral or bilateral TMJ painful clicking, magnetic resonance imaging (MRI) proved disc displacement with reduction (DDWR), refractory to or failed conservative treatment. The patients were divided randomly into two groups (non‐guided and ultrasound (US)‐guided groups). The procedure involved injection of 2 mL solution of a mixture of 0.75 mL 0.9% normal saline solution, 0.3 mL 2% lidocaine and 0.75 mL dextrose 10% using a 25G needle in the joint and 1 mL intramuscular injection to the masseter muscle at the most tender point. The Visual Analogue Score (VAS) was used to compare joint pain intensity over four different periods, beginning with pre‐injection, 1‐, 2‐, and 6‐months postinjection.ResultsTwenty‐two patients 5 males (n = 5/22, 22.7%) and 17 females (n = 17/22, 77.2%) were included in this study. The mean age was 27.3 ± 7.4 years (30.2 ± 7.0) for the non‐guided group and 24.3 ± 6.9 for the US‐guided group. The dextrose injection reduced intensity over time in both groups with statistically significant improvement (P value <.05) at 2 and 6 months in both groups. There was no statistically significant difference in VAS assessment between both groups.ConclusionIntra‐articular injection of dextrose 10% for patients with painful clicking and DDWR resulted in reduced pain intensity in both US‐guided and non‐guided groups with significant symptomatic improvement over time in both groups. US guidance allowed accurate anatomical localization and safe procedure with a single joint puncture.

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Prolotherapy: A new hope for temporomandibular joint pain

Cited by 7 publications

References 4 publications

Dextrose Prolotherapy versus Low Level Laser Therapy (LLLT) for Management of Temporomandibular Joint Disorders (TMD): Clinical Randomized controlled Study

Dextrose Prolotherapy versus Low Level Laser Therapy (LLLT) for Management of Temporomandibular Joint Disorders (TMD): Clinical Randomized controlled Study

Comparative Study Between 2 Types of Prolotherapy in Treatment of Chronic Recurrent Temporomandibular Joint Dislocation

Ultrasound‐Guided Vs Non‐Guided Prolotherapy for Internal Derangement of Temporomandibular Joint. A Randomized Clinical Trial

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