2016
DOI: 10.1016/j.trecan.2016.03.006
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Prolonging Reproductive Life after Cancer: The Need for Fertoprotective Therapies

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Cited by 20 publications
(14 citation statements)
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“… 31 High oestrogen levels cause release of the luteinising hormones which triggers ovulation, which might imply more cycles and rapid depletion of oocytes, consequently leading to an earlier menopause. 32 This can be supported by a recent review study which reported that women with type II diabetes mellitus tend to have an earlier menopause although additional evidence is required to clarify this association. 33 …”
Section: Discussionmentioning
confidence: 86%
“… 31 High oestrogen levels cause release of the luteinising hormones which triggers ovulation, which might imply more cycles and rapid depletion of oocytes, consequently leading to an earlier menopause. 32 This can be supported by a recent review study which reported that women with type II diabetes mellitus tend to have an earlier menopause although additional evidence is required to clarify this association. 33 …”
Section: Discussionmentioning
confidence: 86%
“…The fact that mammalian females are born with the pool of oocytes they will use in their lifetime, represents a challenge since these cells are exposed to several environmental aggressions during the life of the individual that may ultimately harm them. Among others, most cancer therapy treatments are known to produce infertility as a side-effect due to the cessation of follicle pool (Woodard and Bolcun-Filas, 2016). Thus, many efforts are being invested in finding ways to preserve fertility for cancer patients (Woodard and Bolcun-Filas, 2016).…”
Section: Introductionmentioning
confidence: 99%
“…4,5 ). The loss of the PF reserve causes infertility and breakdown of the endocrine function of the ovary, resulting in health impairments such as osteoporosis 6 . In contrast to the PFs, growing follicles are unaffected by a low dosage of irradiation.…”
mentioning
confidence: 99%