Prolonged survival in a patient with choroidal metastases from urothelial bladder cancer

Abstract

Choroidal metastases secondary to urothelial carcinoma are extremely rare and are usually associated with an extremely poor prognosis. We present a case of an 88-year-old man with newly diagnosed urothelial carcinoma of the bladder who presented with acute loss of vision before commencing definitive concurrent chemoradiotherapy to the bladder. Ophthalmological examination demonstrated bilateral choroidal metastases. He received palliative radiotherapy to the orbits and completed his planned radiotherapy to the bladder. He remained disease-free at last follow-up 4 years after the completion of treatment. We review the literature particularly with regard to diagnosis and management of choroidal metastases. Choroidal metastases should be considered in a patient with a history of urothelial cancer presenting with new onset of eye symptoms.

Exudative Retinal Detachment Reveals Metastatic Bladder Cancer

“…4,16Y20 There is a case, however, where a patient with an ocular metastasis from bladder cancer lived for at least 4 years after diagnosis with aggressive treatment. 20 Metastasis to the choroid is the most common source of intraocular malignancy, with the most common site of the primary tumor in the breast, followed by the lung, gastrointestinal tract, and then kidney. 21Y23 Lesions are usually yellow, creamy spotted, and subretinal and found mostly in the posterior pole.…”