Background
Emergency department length-of-stay (ED-LOS) has been associated with worse outcomes after various medical conditions. However, there is a relative paucity of data for ischemic stroke patients. We sought to determine whether a longer ED-LOS is associated with a poor 90-day outcome after ischemic stroke.
Methods
Retrospective analysis of a single-center cohort of consecutive ischemic stroke patients (n=325). Multivariable linear and logistic regression models were constructed to determine factors independently associated with ED-LOS as well as a poor 90-day outcome (modified Rankin scale [mRS] score >2), respectively.
Results
The median ED-LOS in the cohort was 5.8 hours. For patients admitted to the inpatient stroke ward (n=160) versus neurointensive care unit (NICU; n=165), the median ED-LOS was 8.2 hours versus 3.7 hours, respectively. On multivariable linear regression, NICU admission (P<0.001), endovascular stroke therapy (P=0.001), and thrombolysis (P=0.021) were inversely associated with the ED-LOS. Evening shift presentation was associated with a longer ED-LOS (P=0.048). On multivariable logistic regression, a greater admission NIHSS (P<0.001), worse pre-admission mRS (P=0.001), hemorrhagic conversion (P=0.041), and a shorter ED-LOS (P=0.016) were associated with a poor 90-day outcome. Early initiation of statin therapy (P=0.049), endovascular stroke therapy (P=0.041), NICU admission (P=0.029), and evening shift presentation (P=0.035) were associated with a good 90-day outcome.
Conclusions
In contrast to prior studies, a shorter ED-LOS was associated with a worse 90-day functional outcome, possibly reflecting prioritized admission of more severely affected patients who are at high risk for a poor functional outcome.