Prolonged QT interval in ST-elevation myocardial infarction

Abstract

A corrected QT interval peak of at least 480 ms in the acute phase of ST-elevation myocardial infarction is an independent predictor of cardiovascular death. Its association with reduced ejection fraction (≤35%) increases risk stratification accuracy.

Serum β2-Microglobulin Is Closely Associated With the Recurrence Risk and 3-Month Outcome of Acute Ischemic Stroke

“…The results of our study showed that serum β2M levels were significantly and positively correlated with ESRS. Many criteria used to calculate the ESRS, such as myocardial infarction, cardiovascular diseases, peripheral arterial disease, TIA, and cerebral infarction, are among the etiological bases of AIS (30)(31)(32). All of the above studies indicate that β2M may be closely related to the etiology of AIS.…”

Characteristics, predictors and outcomes of new-onset QT prolongation in sepsis: a multicenter retrospective study

“…For a more robust conclusion, multiple models were used in our study to confirm QTP as the independent predictor for 30-day mortality. QTP has been described as a commonly encountered ECG change in a group of heterogeneous diseases such as myocardial infarction [ 31 ], myocarditis [ 32 ] and viral infection [ 33 ]. It was associated with not only ventricular but also AT/AF despite the exclusion of persistent atrial fibrillation, suggesting the potential increase in general electrical vulnerability.…”

Correlation of Prolonged Corrected QT Interval With Ventricular Arrhythmias and In-Hospital Mortality Among ST-Elevation Myocardial Infarction Patients: A Mystique or Lucidity?

“…Additionally, QTc interval prolongation due to an inherent or congenital defect in cardiac channels also plays a fundamental role in contributing to the genetically determined arrhythmogenic state in STEMI [5,7]. This is due to altered electrolyte milieu, disruption of ion channels, and exacerbated sympathetic activity in patients with STEMI [9]. Therefore, careful electrocardiographic and systemic evaluation of such patients remains pivotal to prevent adverse outcomes.…”

“…The difference in the prevalence of VAs might be due to the difference in management strategies as most patients in our clinical setting received thrombolytic therapy that significantly elevates the risk of reperfusion arrhythmias [14]. Moreover, Literature reports that patients receiving thrombolytic therapy have an increased likelihood of developing VAs than patients that received reperfusion therapy via PCI [9]. Nonetheless, VAs can still occur during the acute phase of STEMI even with early and effective reperfusion therapy [15].…”

“…On the contrary, the prolonged QTc represents the extended period of liability to progress to life-threatening arrhythmias. Furthermore, congenital or acquired prolonged QTc interval has also been associated with poor prognostic outcomes (thromboembolism, VAs, heart failure, and mortality) in STEMI patients [9].…”