Prolonged Oral Administration of Ethyl Alcohol Leads to Histopathology of the Epididymis and Seminal Vesicle and Changes of Metabolite Composition in the Tissue Lumen
Chayakorn Taoto,
Nareelak Tangsrisakda,
Wipawee Thukhammee
et al.
Abstract:Prolonged ethanol (EtOH) consumption is associated with male infertility with a decreased spermatogenesis rate as one cause. Defective maturation and development of sperm during their storage in the cauda epididymis and transit in the seminal vesicle can be another cause, possibly occurring before the drastic spermatogenesis disruption. Herein, we demonstrated that the cauda epididymis and seminal vesicle of rats, orally fed with EtOH under a regimen that spermatogenesis was still ongoing, showed histologica… Show more
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