Prolonged Mechanical Ventilation After CABG: Risk Factor Analysis

Gümüş, Funda; Polat, Adil; Yektaş, Abdülkadir; Totoz, Tolga; Bağcı, Murat; Erentuğ, Vedat; Alagöl, Ayşin

doi:10.1053/j.jvca.2014.09.002

Cited by 45 publications

(65 citation statements)

References 25 publications

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“…Elongated time of cardio-pulmonary bypass is of significant importance here and contributes to longer extubation time. After 82.5 minutes, every single minute rise in pumping time increased the late extubation time for 3.5 percent [3]. The results of this research are also in line with those we have achieved.…”

Section: Discussionsupporting

confidence: 91%

“…Early extubation is a terms used to describe the process of extubation within the first 6 to 8 hours after operation. Although the majority of patients who have experienced early extubation have less cardiac and background diseases, this process is not far from possible among patients suffering from several chronic background diseases [3,4,5]. Early extubation has a major influence on improving eyelash functioning, mucosal transport, reduced incidence of pneumonia, lung atelectasis and other pulmonary complications.…”

Section: Introductionmentioning

confidence: 99%

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Studying the Effects of the Length of Using Cardiopulmonary Pump on Early Extubation Following the Operation among Patients Candidated for Coronary Artery Bypass Graft

Kamali¹,

Rostami²,

Nouruzi³

2018

Eurasian J Anal Chem

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Prolonged mechanical ventilation is a really important complication among patients candidated for coronary artery bypass grafting. It also accounts for higher death toll, longer periods of hospitalization, and reduced life quality of patients. As a result, early extubation is a common desire among these patients. One of the factors affecting this process is the length of utilizing pump. The present research seeks to study the effect of the length of utilizing pump on the length of extubation among patients undergoing coronary artery bypass grafting. This is a cross sectional -analytical research conducted on 360 patients candidated for CABG selected based upon the inclusion criteria. The length of pump utilization and Aorta cross clamp, and the length of extubation since entering ICU (after they were moved to ICU) were recorded in research questionnaires and the resulting information was finally analyzed. As it turned out, a longer period of hospitalization would result in a significantly longer time of extubation for patients. The average extubation time for those patients who were under pumping for more than 120 minutes was longer than 2 hours (P = 0.01). A longer period of pumping was significantly associated with higher mortality rates and a linear correlation is observed between these two variables. The mean length of pumping among those patients who had passed away was 169.8 ± 7.8 minutes (P = 0.0001). A study of these patients illustrated the fact that as the length of using pump grows longer, the possibility of atrial fibrillation also goes up (P = 0.01). Longer use of pump results in longer extubation time and causes late extubation.

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Studying the Effects of the Length of Using Cardiopulmonary Pump on Early Extubation Following the Operation among Patients Candidated for Coronary Artery Bypass Graft

Kamali¹,

Rostami²,

Nouruzi³

2018

Eurasian J Anal Chem

View full text Add to dashboard Cite

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“…The rate of neurological complications in patients with prolonged mechanical ventilation (PMV) was 34.8%, while in the group without PMV was 5.4% (p = 0.001). The rate of nosocomial infection in patients with PMV was 34.8%, while in the remaining was 7.5% 17 .…”

Section: Discussionmentioning

confidence: 87%

“…Ventilatory support in the acute phase of TBI is critical to prevent secondary lung injury as comorbidity, and it can promote the stabilization of parameters of cerebral perfusion and adequacy of brain hemodynamics 17 . However, it should be mentioned that the mechanical ventilation time was an independent predictor for intra-hospital mortality after multivariate analysis (p = 0.002).…”

Section: Discussionmentioning

confidence: 99%

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Hemotransfusion and mechanical ventilation time are associated with intra-hospital mortality in patients with traumatic brain injury admitted to intensive care unit

Almeida¹,

Rodrigues

Lemos

et al. 2016

Arq. Neuro-Psiquiatr.

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Objective To identify the factors associated with the intra-hospital mortality in patients with traumatic brain injury (TBI) admitted to intensive care unit (ICU). Methods The sample included patients with TBI admitted to the ICU consecutively in a period of one year. It was defined as variables the epidemiological characteristics, factors associated with trauma and variables arising from clinical management in the ICU. Results The sample included 87 TBI patients with a mean age of 28.93 ± 12.72 years, predominantly male (88.5%). The intra-hospital mortality rate was of 33.33%. The initial univariate analysis showed a significant correlation of intra-hospital death and the following variables: the reported use of alcohol (p = 0.016), hemotransfusion during hospitalization (p = 0.036), and mechanical ventilation time (p = 0.002). Conclusion After multivariate analysis, the factors associated with intra-hospital mortality in TBI patients admitted to the intensive care unit were the administration of hemocomponents and mechanical ventilation time.

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Factors causing prolonged mechanical ventilation and peri-operative morbidity after robot-assisted coronary artery bypass graft surgery

2018

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Robot-assisted coronary artery bypass graft [robot-assisted (coronary artery bypass grafting (CABG)] surgery is the latest treatment for coronary artery disease. However, the surgery extensively affects cardiac and pulmonary function, and the risk factors associated with peri-operative morbidity, including prolong mechanical ventilation (PMV), have not been fully examined. In this retrospective cohort study, a total of 382 patients who underwent robot-assisted internal mammary artery harvesting with mini-thoracotomy direct-vision bypass grafting surgery (MIDCABG) from 2005 to 2012 at our tertiary care hospital were included. The definition of PMV was failure to wean from mechanical ventilation more than 48 h after the surgery. Risk factors for PMV, and peri-operative morbidity and mortality were analyzed with a multivariate logistic regression model. Forty-three patients (11.3%) developed PMV after the surgery, and the peri-operative morbidity and mortality rates were 38 and 2.6%, respectively. The risk factors for PMV were age, left ventricular ejection fraction (LVEF), the duration of one-lung ventilation for MIDCABG (beating time), and peak airway pressure at the end of the surgery. Furthermore, age and anesthesia time were found to be independent risk factors for peri-operative morbidity, whereas age, LVEF, and anesthesia time were the risk factors for peri-operative mortality. These findings may help physicians to properly choose patients for this procedure, and provide more attention to patients with higher risk after surgery to achieve better clinical outcomes.

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Prolonged Mechanical Ventilation After CABG: Risk Factor Analysis

Cited by 45 publications

References 25 publications

Studying the Effects of the Length of Using Cardiopulmonary Pump on Early Extubation Following the Operation among Patients Candidated for Coronary Artery Bypass Graft

Studying the Effects of the Length of Using Cardiopulmonary Pump on Early Extubation Following the Operation among Patients Candidated for Coronary Artery Bypass Graft

Hemotransfusion and mechanical ventilation time are associated with intra-hospital mortality in patients with traumatic brain injury admitted to intensive care unit

Factors causing prolonged mechanical ventilation and peri-operative morbidity after robot-assisted coronary artery bypass graft surgery

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