Prolonged interval between sentinel pseudotumoral demyelination and development of primary CNS lymphoma

Ng, Serena; Butzkueven, Helmut; Rowe, Christopher C.

doi:10.1016/j.jocn.2006.05.003

Cited by 36 publications

(29 citation statements)

References 9 publications

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“…Lymphoma was mentioned on the radiological repot as the most likely or one of the possible diagnoses in 57% of cases. 7 And this case MRI revealed right frontal lobed mass 30x25 mm. enhanced heterojen and intensely after contrast injection.…”

Section: Discussionmentioning

confidence: 55%

“…Nearly all primary CNS lymphomas in immunodeficient patients are associated with EBV or HIV infections. 1,5,6,7,8,9,10 Although our patient was did not have any of the clinical symptoms that would suggest immunodeficiency.…”

Section: Discussionmentioning

confidence: 59%

“…7,8,9,12 The differential diagnosis of PCNSL includes glioma, metastasis, pseudo tumoural multiple sclerosis, brain abscess, subacute infarct, neurosarcoidosis, langerhans histocytosis, CNS infection (cytomegalovirus, toxoplasmosis, etc.). 8,9,10,11 CT and MRI imaging studies due to its hypercellularity, high nuclear/cytoplasmic ratio.…”

Section: Discussionmentioning

confidence: 99%

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Primary intracerebral lymphoma: Case report

Eser

Şahin²,

Korkmaz³

et al. 2012

J Clin Exp Invest

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ÖZETBurada magnetic rezonans görüntüleme (MRG) bulguları ile yüksek dereceli glioma ile karışabilecek olan bir primer merkezi sinir sistemi lenfoması (PMSL) sunuyoruz. Primer merkezi sinir sistemi lenfoması nadir bir tümördür ve intracranial tümörlerin % 0.3-3'ünü oluşturur. Altmış bir yaşında kadın hasta kliniğimize ciddi baş ağrısı, kusma, sol hemiparezi ve geçici bilinç kaybı ile getirildi. Primer merkezi sinir sistemi lenfoması çeşitli biyolojik ve radyolojik özellikler gösterebilir. Burada PMSL'nin MRG bulgularının yüksek dereceli glioma ile karışmasını vurguladık.Anahtar kelimeler: Primer merkezi sinir sistemi lenfoması, yüksek dereceli glioma, B-hücre, tanı ABSTRACTWe describe a case of primary central nervous lymphoma (PCNSL) that may be confused with magnetic resonance imaging (MRI) findings of high grade glioma. Primary central nervous lymphoma is a rare tumour and it account for 0.3-3% of intracranial tumours. A 61 year's old woman was admitted to our clinic with a severe headache, vomiting, left hemiparesia and transient loss of consciousness. Primary central nervous lymphoma may show various biological and radiological characteristics. We herein emphasized being confused with MRI findings of PCNSL and high grade glioma. J Clin Exp Invest 2012; 3 (3): 409-411

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Section: Discussionmentioning

confidence: 55%

Section: Discussionmentioning

confidence: 59%

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Primary intracerebral lymphoma: Case report

Eser

Şahin²,

Korkmaz³

et al. 2012

J Clin Exp Invest

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“…Polyclonal inflammatory cells in the brain may transform to monoclonal PNCSL. This theory is supported by occasional reports of "sentinel lesions" which are biopsy-proven demyelinating or non-neoplastic lesions but ultimately lead to PCNSL months to years later (Alderson et al, 1996;Ng et al, 2007;Yang & Wu., 2007;Habek et al, 2008). However, infectious or inflammatory CNS diseases are rarely reported preceding PCNSL (Deckert & Paulus, 2007).…”

Section: Pathogenesismentioning

confidence: 85%

Primary Central Nervous System Lymphoma

Thaipisuttikul¹,

Nol²

2011

Management of CNS Tumors

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“…1 Authors have reported a case of a young female patient who initially experienced an episode of neurological symptoms caused by histologically proven demyelinating lesion, and who after four years of remission developed primary central nervous system lymphoma (PCNSL). The conclusion was made that demyelinating lesions of the central nervous system (CNS) may precede development of PCNLS for more than four years.…”

Section: Sirmentioning

confidence: 99%