Prolonged extracorporeal oxygenation for cardiorespiratory failure after tetralogy correction

Soeter, John R.; Mamiya, Richard T.; Sprague, Arthur Y.; McNamara, John J.

doi:10.1016/s0022-5223(19)40621-1

Cited by 66 publications

(11 citation statements)

References 3 publications

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“…Despite many serious complications, the patient eventually made a satisfactory recovery. have reported other successes in near fatal respiratory failure following fat emboli and open heart surgery, while Soeter et al (1973) have described survival in cardio-respiratory failure following the correction of a tetralogy of Fallot.…”

Section: Extracorporeal Oxygenation Of the Blood In Acute Respiratorymentioning

confidence: 99%

Editorial

1974

Anaesth Intensive Care

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Section: Extracorporeal Oxygenation Of the Blood In Acute Respiratorymentioning

confidence: 99%

Editorial

1974

Anaesth Intensive Care

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“…However, the Extracorporeal Life Support Organization reports a 31% survival in patients with hypoplastic left heart syndrome (HLHS) undergoing stage I Norwood repair who require mechanical support [7]. Moreover, the survival statistics after ECMO support following cardiac surgery (approximately 50% for infants and 15% for adults) have not been very encouraging and have remained static since its inception in 1973 [8–10]. It has become a major topic in the study of improving the survival rate of patients who need ECMO support after cardiac surgery with postoperative heart failure.…”

Section: Introductionmentioning

confidence: 99%

Outcomes of early versus delayed initiation of extracorporeal life support in cardiac surgery

Pan

Wang

et al. 2019

J Cardiothorac Surg

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Background Extracorporeal membrane oxygenation offers temporary hemodynamic support for patients with refractory cardiogenic shock after cardiovascular surgery. However, the initiation time for such patients is controversial. Changing the initiation time might improve the outcomes. This study aimed to investigate whether early extracorporeal membrane oxygenation could improve postoperative outcomes in patients at a high risk of cardiogenic shock. Methods In this retrospective study, 173 patients with cardiovascular diseases at a high risk of refractory cardiogenic shock which assessed via empirical risk evaluation from 2010 to 2017 were included. After propensity matching, 36 patients, who were matched to patients initiated with extracorporeal membrane oxygenation after cardiovascular operation (delayed extracorporeal membrane oxygenation group, n = 36), were also initiated with such early in the operating room (early extracorporeal membrane oxygenation group, n = 36). The primary outcome was death. The secondary outcomes included receiving continuous renal replacement therapy, ventricular arrhythmia, and pulmonary infection. Results The demographic and baseline variables were similar between the matched groups. The early extracorporeal membrane oxygenation group showed lower mortality (69.44% vs 41.67%, P = 0.03), pulmonary infection morbidity (86.11% vs 55.56%, P < 0.01), and continuous renal replacement therapy rate(88.89% vs 66.67%, P = 0.04). Moreover, they showed improved cardiac index ( P = 0.01) and lactate clearance ( P < 0.01). Conclusions Extracorporeal membrane oxygenation provides effective support for cardiogenic failure refractory to medical management; early initiation improves cardiac output and promotes lactate clearance, thus increasing survival in patients with cardiogenic shock after cardiovascular surgery. Trial registration This is a retrospective study. It was not registered.

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“…The epidemiology of pediatric extracorporeal membrane oxygenation (ECMO) support in infants and children has undergone dramatic changes since the first ECMO case reports in the 1970's ( 1 , 2 ). ECMO technology was used overwhelmingly in neonates in the first decades of its development, primarily for indications such as meconium aspiration syndrome, persistent pulmonary hypertension of the newborn, and respiratory distress syndrome.…”

Section: Introductionmentioning

confidence: 99%

Pediatric ECMO Research: The Case for Collaboration

2018

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The use of extracorporeal membrane oxygenation (ECMO) in the pediatric age has increased considerably in the last decade, as has the complexity of cases and the variety of indications outside of the neonatal age. However, no randomized controlled trials have been attempted to date to test ECMO as an intervention in non-neonatal pediatric patients with critical illness. In this review, we provide a brief overview of the history of clinical research in pediatric ECMO and discuss methodological challenges including heterogeneity of ages and diagnoses in the pediatric ECMO population, rapid advances in technology and clinical practice related to ECMO, feasibility of enrolling critically ill children on ECMO in clinical research studies, and variability in ECMO management across institutions and countries. Lastly, we discuss opportunities and existing infrastructure for future multicenter, multi-network research collaborations for pediatric ECMO studies.

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Prolonged extracorporeal oxygenation for cardiorespiratory failure after tetralogy correction

Cited by 66 publications

References 3 publications

Editorial

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Outcomes of early versus delayed initiation of extracorporeal life support in cardiac surgery

Pediatric ECMO Research: The Case for Collaboration

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