Prolonged evolution of a lentigo maligna

Bevona, Caroline; Liu, Vincent; Sober, Arthur J.

doi:10.1016/j.jaad.2002.09.002

Cited by 5 publications

(2 citation statements)

References 30 publications

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“…The absence of an invasive component, particularly in an LM first documented at the age of 22 years and excised 29 years later, can be considered to be another peculiar finding of our patient. Bevona et al [7] reported LM melanoma developing approximately 40 years after the first onset of LM, but this case differs from ours inasmuch as it was characterized by multiple recurrences after previous surgical and nonsurgical treatments.…”

Section: Commentcontrasting

confidence: 68%

Lentigo Maligna in a Young Adult

et al. 2008

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Background: Lentigo maligna is mainly diagnosed in the elderly with severely sun-damaged skin. Observation: We describe a case of lentigo maligna in a 51-year-old woman with Fitzpatrick skin type III. Based on private photographs of the patient, we were able to ascertain that the lesion was already present at the age of 22 years. Despite the 29-year clinical history, the lesion was still entirely intraepidermal on histologic examination. Conclusion: Lentigo maligna in young adults is extremely rare, and therefore represents a diagnostic challenge for both clinicians and histopathologists.

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Section: Commentcontrasting

confidence: 68%

Lentigo Maligna in a Young Adult

et al. 2008

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“…Second, anti‐CD117 therapies, such as STI‐571 (Gleevec ® ), may be used as an adjuvant therapy for primary superficial spreading melanomas, including lentigo maligna melanoma (LMM) and melanoma in situ . Surgical excision will remain the treatment of choice in these cases, but often it is challenging to achieve a true negative margin and the recurrence rate for LMM is very high 18 . An anti‐CD117 agent will help turn off the proliferative signal and hopefully induce apoptosis of atypical melanocytes as observed in vitro 19 .…”

Section: Discussionmentioning

confidence: 99%

Expression of c‐kit (CD117) in Spitz nevus and malignant melanoma

Zhu

Fitzpatrick

2005

J Cutan Pathol

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Melanoma Incidence in Czech Republic, the Relation between Histology, Body Site of Melanoma, and Duration of Lesions

Čelakovská

Bukač

Čáková

et al. 2020

Acta Med. (Hradec Kralove, Czech Repub.)

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Aim: To evaluate the occurrence of melanoma in the period 1996–2017 in East Bohemia region in the Czech Republic. Method: We studied the incidence of melanoma and the age of diagnosis (adjusted calculation) and the parameters such as histology, body site of lesions, the length of the duration of lesions in 2810 patients. Results and conclusion: No change in the occurrence of melanoma and in age of melanoma during this period was found. The difference between men and women was not confirmed in histology, but the difference between men and women was confirmed in the body site of lesion and in the length of duration of lesion. No relation between the length of duration of lesions from which melanoma had originated and its histology was confirmed. The relation was confirmed between histology and body site of melanoma. The relation between the body site and the length of duration of previous lesions was confirmed also. The increasing occurrence of melanoma on the trunk according to the duration of the previous lesions was confirmed.

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Prolonged evolution of a lentigo maligna

Cited by 5 publications

References 30 publications

Lentigo Maligna in a Young Adult

Lentigo Maligna in a Young Adult

Expression of c‐kit (CD117) in Spitz nevus and malignant melanoma

Melanoma Incidence in Czech Republic, the Relation between Histology, Body Site of Melanoma, and Duration of Lesions

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