2019
DOI: 10.1111/tmi.13291
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Prolonged and persistent diarrhoea is not restricted to children with acute malnutrition: an observational study in Ethiopia

Abstract: Objectives To assess the prevalence of prolonged and persistent diarrhoea, to estimate their co‐occurrence with acute malnutrition and association with demographic and clinical factors. Methods Case–control study where cases were children under 5 years of age with diarrhoea and controls were children without diarrhoea, frequency‐matched weekly by age and district of residency. Controls for cases 0–11 months were recruited from vaccination rooms, and controls for cases 12–59 months were recruited by house visit… Show more

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Cited by 5 publications
(6 citation statements)
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“…This included 1216 children aged 0–23 months, of whom 59 were cases with cryptosporidiosis, 432 cases with NCrD, and 725 controls. For details of screening, eligibility, and inclusion, see previous works [ 26 , 29 ] and the study flowchart ( Fig 2 ).…”
Section: Resultsmentioning
confidence: 99%
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“…This included 1216 children aged 0–23 months, of whom 59 were cases with cryptosporidiosis, 432 cases with NCrD, and 725 controls. For details of screening, eligibility, and inclusion, see previous works [ 26 , 29 ] and the study flowchart ( Fig 2 ).…”
Section: Resultsmentioning
confidence: 99%
“…MAM was less strongly associated with cryptosporidiosis than SAM but was far more common. The WHO provides no specific guidance for the management of diarrhoea in children with MAM, besides the promotion of supplementary foods [ 29 , 35 ]. Regrettably, most Ethiopian children with MAM, including in our study area, are excluded from supplementary feeding programmes, as they reside within areas that are not classified as food insecure [ 36 ].…”
Section: Discussionmentioning
confidence: 99%
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“…Community controls without diarrhoea in the previous 48 h were recruited by weekly frequency matching by geographical district of the household, age group, and enrolment week. 23 Jimma University Institutional Review Board (reference RPGC/610/2016), the Ethiopian National Research Ethics Review Committee (reference JU JURPGD/839/2017), and the Regional Committee for Medical and Health Research Ethics of Western Norway (reference 2016/1096) approved the study.…”
Section: Study Design and Participantsmentioning
confidence: 99%
“…Diarrhea is a highly prevalent and bothersome disorder and a severe worldwide public health issue, especially in developing countries ( Thapar and Sanderson, 2004 ; Zangenberg et al, 2019 ). Lactose malabsorption or intolerance affects 20% of the world population and is frequently associated with diarrheal conditions ( Arasaradnam et al, 2018 ; Hiner and Walters, 2021 ).…”
Section: Introductionmentioning
confidence: 99%