Prolongation of corneal xenograft survival with deoxyspergualin and anti-LFA-1 monoclonal antibody

Yamagami, Satoru; Isobe, Mitsuaki; Yamagami, Hiroko; Hori, Junko; Kaburaki, T.; Tsuru, Tadahiko

doi:10.1016/s0041-1345(97)00331-x

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“…Reports of corneal xenotransplantation models show different results in different species. In guinea pig‐to‐rat corneal xenotransplantation, the mean survival time (MST) was about 3 to 8 days [1], in guinea pig‐to‐mice, 9 to 16 days [3,5,6], and in rat‐to‐mice, 5 to 7 days [7,8]. But in a human‐to‐monkey model, most corneal grafts retained clarity for more than 6 months [9].…”

Section: Introductionmentioning

confidence: 99%