Proliferative pancreatic cysts: Pathogenesis and treatment options

Hoover, Eddie L.; Natesha, R.; Đào, Anh; Adams, Carlton Z.; Barnwell, Sydney

doi:10.1016/0002-9610(91)90087-t

Cited by 15 publications

(9 citation statements)

References 9 publications

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“…Potential long-term survivors among pancreatic malignancies are to be found in the group of patients with mucinous cystic tumors subjected to surgical resection [3, 19, 20]. In patients where preoperative investigations have indicated a potential mucinous cystic tumor of the pancreas, management should be directed against obtaining the entire cyst wall for complete histological examination [21, 22].…”

Section: Discussionmentioning

confidence: 99%

“…Cystic neoplasms of the pancreas are also uncommon and account for 10–15% of all pancreatic cysts and only 1% of pancreatic malignancies [2, 3], the majority of pancreatic cystic lesions being pseudocysts without epithelial lining and proliferative potential. Bronchogenic cysts located below the diaphragm are very rare and normally not encountered among differential diagnoses in patients with cystic neoplasms of the pancreas.…”

Section: Introductionmentioning

confidence: 99%

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Retroperitoneal Bronchogenic Cyst as a Differential Diagnosis of Pancreatic Mucinous Cystic Tumor

Andersson¹,

Lindell²,

Cwikiel

et al. 2003

Dig Surg

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Cystic tumors of the pancreas where a pseudocyst has not been able to be excluded has been considered potentially proliferative and pre-malignant or malignant and thus aggressive surgical approach has been advocated. Retroperitoneal cystic tumors are rare and among these bronchogenic cysts are extremely infrequent. The present paper describes a case of bronchogenic cyst in association with the pancreas in which diagnostic work-up was not able to exclude a proliferative pancreatic cystic tumor.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Retroperitoneal Bronchogenic Cyst as a Differential Diagnosis of Pancreatic Mucinous Cystic Tumor

Andersson¹,

Lindell²,

Cwikiel

et al. 2003

Dig Surg

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“…It is known that about 90% of all cystic lesions are benign pseudocysts [1,2]. Some 10%, however, are cystic lesions of other origin, showing all stages of cellular differentiation, from benign to highly malignant tumors.…”

Section: Introductionmentioning

confidence: 99%

Cystic Tumors of the Pancreas

Gasslander

Arnelo²,

Albiin

et al. 2001

Dig Dis

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The discovery of a cystic lesion in the pancreas implies a challenge for the physician. Approximately 10% are cystic tumors, benign to highly malignant, or true cysts, showing all stages of cellular differentiation, from benign to highly malignant tumors. Malignant cystic tumors are rare and comprise only about 1% of all pancreatic malignancies, they are potentially curable. Therefore, correct diagnosis and treatment of these lesions are of great importance. It is usually not possible to separate a pseudocyst from a benign cyst or a cystic tumor, but there are some signs and findings that could be helpful in the clinical decision. The diagnosis of a cystic pancreatic tumor requires different imaging techniques, including ultrasonography, computerized tomography, magnetic resonance imaging, and magnetic resonance cholangiopancreatography, but to distinguish a pseudocyst or a benign cyst from a potentially malignant lesion can be very difficult. The usefulness of blood tests and investigations of cyst fluid can be questionable. Today, surgical treatment of cystic pancreatic tumors can be performed with low morbidity. Therefore, we conclude that an active strategy with resection of cystic tumors of the pancreas should be recommended.

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“…. Five-year survival rates in patients with completely excised cystadenocarcinoma vary between 33 and 68% [1][2][3][4][5][6][7]. In contrast, the prognosis in patients with unresected cystadenocarcinoma is poor and similar to that of unresected pancreatic ductal adenocarcinoma [1].…”

mentioning

confidence: 99%

“…Patients with typical asymptomatic serous cystadenomas are not candidates for surgery due to the benign nature [2]. In contrast, mucinous cystadenomas warrant surgical resection because of their malignant potential [3]. The prognosis following resection of benign mucinous cystadenoma is excellent [2].…”

mentioning

confidence: 99%