Proliferation zones in the brain of adult fish Austrolebias (Cyprinodontiform: Rivulidae): a comparative study

Fernández, Ana María González; Rosillo, Juan Carlos; Casanova, Gabriela; Olivera-Bravo, Silvia

doi:10.1016/j.neuroscience.2011.05.063

Cited by 36 publications

(35 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Continued cell proliferation in this area during adulthood has been found in all teleostean species examined thus far-the brown ghost knifeWsh (Zupanc and Horschke 1995), the three-spined stickleback (Ekström et al 2001), the zebraWsh (Zupanc et al 2005;Grandel et al 2006), three species of killiWshes (Fernández et al 2011), and, as shown in the present study, the Mozambique tilapia (Fig. 3d).…”

Section: Discussionsupporting

confidence: 83%

“…This Wgure underscores the important role that teleosts play for a comparative understanding of adult neurogenesis. Detailed mappings of the proliferation zones in the whole brain have been performed in several species: the brown ghost knifeWsh (Zupanc and Horschke 1995), a member of the taxonomic order of the Gymnotiformes; the threespined stickleback (Ekström et al 2001), a member of the Gasterosteiformes; the zebraWsh (Zupanc et al 2005;Grandel et al 2006), a member of the Cypriniformes; the killiWsh (Fernández et al 2011), a member of the Cyprinodontiformes; and the Mozambique tilapia (present paper), a member of the Perciformes.…”

Section: Cellular Diverentiationmentioning

confidence: 99%

“…First, in each species the number of new cells generated in the adult brain, relative to the total number of brain cells, is tremendous and at least one, if not two orders of magnitude higher than in the adult mammalian brain (Zupanc and Horschke 1995;Hinsch and Zupanc 2007). Second, these adult-born cells arise from stem cells/progenitors located in several dozens of speciWc proliferation zones, which, although present in all major subdivisions of the brain, are primarily concentrated in the telencephalon, diencephalon, mesencephalon, and cerebellum (Zupanc and Horschke 1995;Ekström et al 2001;Zupanc et al 2005;Grandel et al 2006;Pellegrini et al 2007;Kaslin et al 2009;Alunni et al 2010;Ganz et al 2010;Rothenaigner et al 2011;Chapouton et al 2011;Fernández et al 2011). By contrast, only two proliferation zones have been found consistently in the adult mammalian brain.…”

Section: Cellular Diverentiationmentioning

confidence: 99%

“…(Fernández et al 2011). Very little is known about other key taxonomic groups, such as the perch-like Wshes (Perciformes), which, with over 7,000 species, are one of the largest vertebrate orders.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Adult neurogenesis in the brain of the Mozambique tilapia, Oreochromis mossambicus

et al. 2012

View full text Add to dashboard Cite

Although the generation of new neurons in the adult nervous system ('adult neurogenesis') has been studied intensively in recent years, little is known about this phenomenon in non-mammalian vertebrates. Here, we examined the generation, migration, and differentiation of new neurons and glial cells in the Mozambique tilapia (Oreochromis mossambicus), a representative of one of the largest vertebrate taxonomic orders, the perciform fish. The vast majority of new cells in the brain are born in specific proliferation zones of the olfactory bulb; the dorsal and ventral telencephalon; the periventricular nucleus of the posterior tuberculum, optic tectum, and nucleus recessi lateralis of the diencephalon; and the valvula cerebelli, corpus cerebelli, and lobus caudalis of the cerebellum. As shown in the olfactory bulb and the lateral part of the valvula cerebelli, some of the young cells migrate from their site of origin to specific target areas. Labeling of mitotic cells with the thymidine analog 5-bromo-2'-deoxyuridine, combined with immunostaining against the neuron-specific marker protein Hu or against the astroglial marker glial fibrillary acidic protein demonstrated differentiation of the adult-born cells into both neurons and glia. Taken together, the present investigation supports the hypothesis that adult neurogenesis is an evolutionarily conserved vertebrate trait.

show abstract

Section: Discussionsupporting

confidence: 83%

Section: Cellular Diverentiationmentioning

confidence: 99%

Section: Cellular Diverentiationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Adult neurogenesis in the brain of the Mozambique tilapia, Oreochromis mossambicus

et al. 2012

View full text Add to dashboard Cite

show abstract

“…Within the killifish genus Austrolebias, a species (A. affinis) that relies most heavily on visual communication during courtship has an especially high rate of cell proliferation in visual areas of the brain (optic tectum and torus longitudinalis) and a low rate in the olfactory bulb, while another species that uses chemical signals (A. reicherti) in courtship shows the reverse pattern [Fernández et al, 2011]. Thus, during the evolution of this clade, it appears that brains are most plastic in regions that have the most crucial functions in sexual behavior.…”

Section: Modality-specific Environmental Influencesmentioning

confidence: 99%

Fish Neurogenesis in Context: Assessing Environmental Influences on Brain Plasticity within a Highly Labile Physiology and Morphology

Dunlap¹

2016

Brain Behav Evol

View full text Add to dashboard Cite

Fish have unusually high rates of brain cell proliferation and neurogenesis during adulthood, and the rates of these processes are greatly influenced by the environment. This high level of cell proliferation and its responsiveness to environmental change indicate that such plasticity might be a particularly important mechanism underlying behavioral plasticity in fish. However, as part of their highly labile physiology and morphology, fish also respond to the environment through processes that affect cell proliferation but that are not specific to behavioral change. For example, the environment has nonspecific influences on cell proliferation all over the body via its effect on body temperature and growth rate. In addition, some fish species also have an unusual capacity for sex change and somatic regeneration, and both of these processes likely involve widespread changes in cell proliferation. Thus, in evaluating the possible behavioral role of adult brain cell proliferation, it is important to distinguish regionally specific responses in behaviorally relevant brain nuclei from global proliferative changes across the whole brain or body. In this review, I first highlight how fish differ from other vertebrates, particularly birds and mammals, in ways that have a bearing on the interpretation of brain plasticity. I then summarize the known effects of the physical and social environment, sex change, and predators on brain cell proliferation and neurogenesis, with a particular emphasis on whether the effects are regionally specific. Finally, I review evidence that environmentally induced changes in brain cell proliferation and neurogenesis in fish are mediated by hormones and play a role in behavioral responses to the environment.

show abstract

Brain Atlas of an Emerging Teleostean Model: Nothobranchius furzeri

D’Angelo

2013

The Anatomical Record

View full text Add to dashboard Cite

Nothobranchius furzeri has emerged as a new fish model for neurobiological and age research over recent years, due to the exceptionally short lifespan, age-dependent cognitive/behavioral decline, expression of agerelated biomarkers. The growing interest in this teleost has raised the need to construct an atlas of the whole brain of N. furzeri. The study has been carried out on adult specimens belonging to the long lived strain, originating from Mozambique and named MZM 04/10. In the atlas, the external features of brain, images of sections stained with luxol fast bleu/violet and schematic drawings of the most representative sections are showed. The identification and description of brain structures has been carried out on methodological and hodological studies. Comparative analyses have

show abstract

Proliferation zones in the brain of adult fish Austrolebias (Cyprinodontiform: Rivulidae): a comparative study

Cited by 36 publications

References 44 publications

Adult neurogenesis in the brain of the Mozambique tilapia, Oreochromis mossambicus

Adult neurogenesis in the brain of the Mozambique tilapia, Oreochromis mossambicus

Fish Neurogenesis in Context: Assessing Environmental Influences on Brain Plasticity within a Highly Labile Physiology and Morphology

Brain Atlas of an Emerging Teleostean Model: Nothobranchius furzeri

Contact Info

Product

Resources

About