Proliferation of Histamine and Serotonin in Mast Cells of Patients With Inflammatory Periodontal Disease in the Course Oft

Abstract

The purpose of this study was to examine the indicators of cell proliferation, apoptosis, as well as the quantitative features of histamine and serotonin producing gum mast cells in patients with chronic gingivitis and periodontitis through the treatment dynamics. The study has shown that gingivitis is associated with hyperplasia and hyperfunction of the gum mast cells general population producing histamine, as well as with an increase in cell proliferation. Periodontitis revealed an increase in apoptosis, a decrease in periodontal proliferation due to hyperplasia and hyperfunction of the total mast cell population secreting histamine and serotonin.