Proliferation of Bifidobacterium L80 under different proportions of milk protein hydrolysate

Abstract

The intestinal microecological environment is critical to an infant's growth. For those infants consuming milk power, it is very important to improve the intestinal microecological environment to promote the healthy growth of infants. In this paper, Milk protein hydrolysate (MPH), consisting of different proportions of proteins and small molecule peptides (5:5, 4:6, 3:7, 2:8, 1:9) were added to infant formula powder (IFP). The effects of MFP-enriched IFP addition on proliferation and metabolism of Bifidobacterium L80 were studied. Compared with MPH-free IFP, MFP-enriched IFP with 1:9 of proteins to small molecule peptides significantly enhanced the proliferation of Bifidobacterium L80, resulting in higher cell density, greater viable counts and higher titratable acidity. MFP-enriched IFP increased the content of seven organic acids and H2O2 in the system, and improved the antibacterial activity to E. coli BL21. This study suggested that MPH could be an effective addition to infant formula powder to promote the growth of Bifidobacterium, so to improve the intestinal health of infants.

Design of a proteolytic module for improved metabolic modeling of Bacteroides caccae

“…High-protein diets have become more frequent over the last 50 years in industrialized countries with recourse to the Western diet and the use of protein-enriched diets for specific indications or populations such as athletes or elderlies. Few studies showed a significant impact of high amounts of dietary proteins on the gut microbiota of adults ( 5 , 33 ), but most of the reports on the effect of high amounts of whey proteins concerned infants showing that these proteins favored the development of Bifidobacterium and Lactobacillus genera ( 34 – 36 ). An in vitro study using stools from healthy 1–3 years old infants reported a significant increase in Bacteroides , Proteobacteria , and Streptococcus relative abundances and a rise in SCFA production ( 37 ).…”

Ulcerative colitis alleviation of colon-specific delivered rhamnolipid/fullerene nanocomposites via dual modulation in oxidative stress and intestinal microbiome

“…Besides, C 60 up-regulates the abundance of probiotics including Lactobacillus, Bifidobacerium and Akkermansia to affect the immune system either directly or indirectly. Moreover, probiotics-produced SCFAs promote not only the recovery of immune system homeostasis and organismal tolerance 61,62 but the self-growth of probiotic microbiota through the establishment of an acidic environment, 63 thereby ensuring the homeostasis of intestinal flora. Inspired by this, we proposed an ''immune-microbiome'' therapeutic strategy (Fig.…”