“…In a study by Tetè et al, polished zirconia showed a better integration in respect to the other materials [58]. Analysis on human epithelial tissue cultures, on the other side, demonstrated that lithium disilicate showed the best biocompatibility when compared to zirconia and cobalt-chromium alloys.…”
The present paper was aimed at reporting the state of the art about lithium disilicate ceramics. The physical, mechanical, and optical properties of this material were reviewed as well as the manufacturing processes, the results of in vitro and in vivo investigations related to survival and success rates over time, and hints for the clinical indications in the light of the latest literature data. Due to excellent optical properties, high mechanical resistance, restorative versatility, and different manufacturing techniques, lithium disilicate can be considered to date one of the most promising dental materials in Digital Dentistry.
“…In a study by Tetè et al, polished zirconia showed a better integration in respect to the other materials [58]. Analysis on human epithelial tissue cultures, on the other side, demonstrated that lithium disilicate showed the best biocompatibility when compared to zirconia and cobalt-chromium alloys.…”
The present paper was aimed at reporting the state of the art about lithium disilicate ceramics. The physical, mechanical, and optical properties of this material were reviewed as well as the manufacturing processes, the results of in vitro and in vivo investigations related to survival and success rates over time, and hints for the clinical indications in the light of the latest literature data. Due to excellent optical properties, high mechanical resistance, restorative versatility, and different manufacturing techniques, lithium disilicate can be considered to date one of the most promising dental materials in Digital Dentistry.
“…Besides, all‐ceramic materials hold other advantages including low plaque retention and optimum biocompatibility inducing favorable biological responses in the soft tissues. In particular, zirconia demonstrated the possibility of inducing an epithelial attachment to its surface . Recent improvements in CAD/CAM technology enable shaping the zirconium dioxide framework with anatomic form.…”
Section: Discussionmentioning
confidence: 99%
“…In particular, zirconia demonstrated the possibility of inducing an epithelial attachment to its surface. 23 Recent improvements in CAD/CAM technology enable shaping the zirconium dioxide framework with anatomic form. Thus a layer of uniform veneering porcelain can be created throughout the framework, substantially reducing the risk of chipping, especially in the posterior area.…”
This manuscript describes an interdisciplinary approach over a period of 8 years combining surgical and prosthodontic treatment of a young patient diagnosed with hypocalcified-type amelogenesis imperfecta and anterior open bite. The treatment procedures included transitional restorations, orthodontic treatment, and maxillofacial surgery with a one-piece Le Fort I osteotomy, bilateral mandibular osteotomy, and genioplasty. The definitive prosthetic rehabilitation consisted of 28 zirconia-based ceramic single crowns restoring both esthetics and function. Photographs and radiographs associated with clinical evaluation were used in the maintenance period. Two-year follow-up revealed satisfactory results and no deterioration in the restorations.
“…To author's knowledge there is no study comparing the attachment and proliferation of HGFs on titanium and on lithium disilicate glass-ceramic. Tetè et al (2014) reported that lithium disilicate glass-ceramic shows a lower cytocompatibility than zirconia and other authors observed that this material shows cytotoxic effects (Brackett et al 2008;Pabst et al 2014).…”
Section: Discussionmentioning
confidence: 99%
“…Actually, titanium is a gold-standard material in the field of dental implant prosthodontics mainly due to its high corrosion resistance, low toxicity, very low allergenic potential and good biocompatibility properties (Jorge et al 2013). Regarding lithium disilicate glassceramic, HGF behavior on this material has been poorly studied (Brackett et al 2008;Pabst et al 2014;Tetè et al 2014). The present results showed a good cellular attachment on lithium disilicate glass-ceramic but a slower proliferation than on titanium.…”
In vitro studies about biomaterials biological properties are essential screening tests. Yet cell cultures encounter difficulties related to cell retention on material surface or to the observation of both faces of permeable materials. The objective of the present study was to develop a reliable in vitro method to study cell behavior on rigid and flexible/permeable biomaterials elaborating two specific insert-based systems (IBS-R and IBS-F respectively). IBS-R was designed as a specific cylindrical polytetrafluoroethylene (PTFE) system to evaluate attachment, proliferation and morphology of human gingival fibroblasts (HGFs) on grade V titanium and lithium disilicate glassceramic discs characteristics of dental prostheses. The number of cells, their covering on discs and their morphology were determined from MTS assays and microscopic fluorescent images after 24, 48 and 72 h. IBS-F was developed as a two components system to study HGFs behavior on guided bone regeneration polyester membranes. The viability and the membrane barrier effect were evaluated by metabolic MTS assays and by scanning electron microscopy. IBS-R and IBS-F were shown to promote (1) easy and rapid handling; (2) cell retention on biomaterial surface; (3) accurate evaluation of the cellular proliferation, spreading and viability; (4) use of non-toxic material. Moreover IBS-F allowed the study of the cell migration through degradable membranes, with an access to both faces of the biomaterial and to the bottom of culture wells for medium changing.
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