Prolapse and sexual function in women with benign joint hypermobility syndrome

Abstract

Objective To determine whether pelvic organ prolapse (POP) and sexual dysfunction are more severe in women with benign joint hypermobility syndrome (BJHS) than in the normal population.Design Case-control study.Setting King's College Hospital NHS Foundation Trust, London, UK and University College Hospital, London, UK.Population Women diagnosed with BJHS (n = 60) at University College Hospital. Control participants (n = 60) recruited from King's College Hospital NHS Foundation Trust.Methods Objective assessment of POP was undertaken using the Pelvic Organ Prolapse Quantification System (POP-Q). Both groups were asked to complete the Prolapse quality of life (P-QOL) and pelvic organ prolapse/urinary incontinence sexual (PISQ-12) questionnaires.Main outcome measures Comparison of vaginal anatomy using POP-Q between the two groups. Comparison of P-QOL and PISQ-12 quality of life scores between the two groups.Results In all, 120 women (60 in Study group, 60 in Control group) were recruited. All women in the study group were matched with healthy control women according to age, parity and ethnicity. There was a statistically significant difference between points Aa, Ba, Ap, Bp and C in study and control groups showing that prolapse is objectively more severe in those with BJHS. Significantly more women with BJHS felt that POP interfered with sex and defecation compared with the control group. The impact of prolapse symptoms on quality of life was statistically different in almost all nine P-QOL domains.Conclusions A large number of women with BJHS have prolapse symptoms, which significantly affect their quality of life. POP is more severe in women with BJHS.

Urogenital and pelvic complications in the Ehlers‐Danlos syndromes and associated hypermobility spectrum disorders: A scoping review

“…Women with EDS or HSD are thought to be at higher risk for POP due to the reliance on collagenous tissues for support of these structures. In this review, most (21/23) studies supported this correlation, reporting associations between hypermobility and POP and higher rates or greater severity of POP in those with EDS or HSD as compared to controls . Two studies reported negative findings.…”

Gastrointestinal disorders in joint hypermobility syndrome/Ehlers‐Danlos syndrome hypermobility type: A review for the gastroenterologist

“…One small study found a high prevalence (75%) of pelvic organ prolapse in women with EDS . Another study demonstrated the frequent occurrence of defecatory problems in patients with JHS/EDS‐HT, most notably straining (61.7%), incomplete evacuation (63%), and digitation (33.3%) . Furthermore, the majority (73.3%) of the JHS/EDS‐HT group had a clinically significant prolapse compared with 35% of the control group ( P <.001).…”

Síndrome De Hipermobilidade Articular Nos Pacientes Com Disfunções Do Diafragma Da Pelve: Revisão De Literatura

“…Porém, o impacto na qualidade de vida não apresenta diferença entre os dois grupos. O estudo também mostrou que, parte significativamente da população de estudo, 61,7%, n= 37 do grupo SHAB, tinha dificuldade para evacuar, existindo maior incidência de prolapso no compartimento posterior (5) . Confirmando esse achado, um estudo investigou a prevalência de SHA na população em geral e em pacientes que se apresentavam para investigação fisiológica anorretal.…”

“…É ocasionada pela frouxidão ou comprimento excessivo do tecido, que leva ao aumento da amplitude de movimento além do normal, e pode estar acompanhada de queixas dolorosas (1) . Descrita pela primeira vez em 1967, a Síndrome de Hipermobilidade Articular (SHA) identifica-se pela associação da Hipermobilidade Articular (HA) com doenças musculoesqueléticas (2) e é caracterizada como uma desordem hereditária do tecido conectivo que pode desencadear luxação, subluxação, artralgia, artrite, tendinite, tenossinovite, ligamentos danificados e fraturas, existindo associação com dor nas articulações e instabilidade (5) e, geralmente, é avaliada utilizando-se os critérios de Brighton, que inclui a pontuação de Beighton (6) . Os critérios de Brighton são divididos em critérios maiores e critérios menores.…”