Prolactin, Phenothiazines, Admission to Mental Hospital, and Carcinoma of the Breast

New HSP27 inhibitors efficiently suppress drug resistance development in cancer cells

“…Chlorpromazine has also been used as antipsychotic drug to treat pain and side effects in advanced cancer [ 40 ]. There are reports dating back over 40 years, which suggest that psychiatric patients taking chlorpromazine have lower incidence of breast cancer [ 41 ]. Recently, Yde et al .…”

Depressive symptoms and muscular fitness contribute independently to the ability to perform daily life activities in people with bipolar disorder

“…The majority of the studies investigating the influence of antipsychotic medication on breast cancer risk have considered patients treated with FGA. These studies (Brugmans et al 1973, Dalton et al 2006, Kanhouwa et al 1984, Kelly et al 1999, Wagner & Mantel 1978 have not found an increased risk of breast cancer, an exception being the cohort study by Wang et al (2002). These researchers conducted a retrospective cohort study in more than 100,000 women (including psychiatric patients as well as medical patients and patients from nursing homes) in which the relationship between FGA (and the SGA risperidone) and breast cancer risk was investigated.…”

Mammography stages of change in middle-aged women with schizophrenia: An exploratory analysis

“…Moreover, older women with psychosis may be at increased risk for breast cancer because of factors related to their psychiatric disorder or its treatment. Some [ 14 - 16 ], but not all [ 17 - 21 ], studies have found an increased risk of breast cancer in women with schizophrenia, the reasons for which are not yet clear. This may, in part, be due to the fact that women with schizophrenia are more likely to have the general risk factors commonly associated with increased incidence of breast cancer, such as nulliparity, obesity, high fat diet, or physical inactivity [ 22 , 23 ].…”