“…The global prevalence of hip fracture has been forecast to rise in line with demographic changes in population, and the median age at which patients present is currently rising in Northern Europe (by about 1 year of age every 5 years) [64]. In addition to high peri-operative mortality and morbidity, hip fracture is associated with extensive, expensive rehabilitation and loss of independence, and more commonly if patients experience delay before surgery, inadequate analgesia, blood loss, dehydration, unsympathetic anaesthesia, surgical stress, malnourishment and hypoxia, or secondary complications, such as delirium, pneumonia, cardiac failure, thromboembolism and wound infection [65].…”