Progressive systemic sclerosis and autoimmune haemolytic anaemia

Abstract

Quantitation of thermography in arthritis using multi-isothermal analysis. II. Effect of non-steroidal antiinflammatory therapy on the thermographic index.

A case of systemic sclerosis complicated by autoimmune hemolytic anemia

“…However, among the cases of SSc complicated by AIHA, a considerable number of cases of the limited cutaneous type have been reported. 1,4,5,7,[10][11][12]15 In addition, there have been several cases with cold agglutinin, 1,2,4,7,13,16 thrombocytopenia Congestive heart failure and interstitial pneumonitis were seen on chest computed tomography on admission (including autoimmune thrombocytopenia), 4,9,11,14 or IgA deficiency; 9,10 none of these conditions were observed in this case. All three reported cases with elevated serum IgM levels had cold agglutinin, 2,7,13 but the present case did not have cold agglutinin despite the elevated serum IgM level.…”

“…However, less than 20 cases of SSc with AIHA have been reported (Table 2). [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16] The possibility of an overlap with systemic lupus erythematosus (SLE) should always be considered in such cases of SSc complicated by AIHA. Although the hematological disorder (AIHA and lymphopenia) and the weakly positive anti-RNP antibody and lupus anticoagulant in this case were suggestive of SLE, she had not been diagnosed as having SLE because of the lack of other characteristic symptoms and findings.…”

Auto-Immune Haemolytic Anaemia and Thrombocytopenia in Scleroderma

“…Since the first report of auto-immune haemo lytic anaemia in scleroderma by Fudenberg and Wintrobe [3] in 1955, only about 10 cases have been re corded [1,2,[4][5][6][7][8][9], and auto-immune thrombocytope nia seems to be even rarer. The combination of auto immune haemolytic anaemia and auto-immune thrombocytopenia has previously been described in only 1 patient with scleroderma [6].…”