Progressive perioperative benefits of laparoscopy in combination with an ERAS (Enhanced Recovery After Surgery) protocol in radical cystectomy with ileal conduit

Domínguez, A.; Muñoz-Rodríguez, J.; Martos, R.; Parejo, V.; Prera, A.; Tremps, C.; Bonfill, Teresa; Pino, C. del; Augé, Axel; Prats, J.

doi:10.1016/j.acuroe.2020.10.012

Cited by 3 publications

(2 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There is a lack of evidence regarding this type of surgery, and the study in question mainly included patients in a state of malnutrition before surgery, although there was no difference regarding the use of neoadjuvant chemotherapy or radiotherapy before surgery. Another limitation of these studies is the presence of an ERAS protocol, or lack thereof, in the study’s development [ 47 ].…”

Section: Discussionmentioning

confidence: 99%

“…In the last few years, the studies conducted regarding immunonutrition without an ERAS protocol have shown similar data to that collected in previous research, with a decrease in inflammatory markers and no effect on clinical features [ 23 , 24 ]. Recently, the potential use of immunonutrition in ERAS protocols has been studied, and it has been recommended by many societies as an intervention preceding this type of surgery to reduce the rate of patient complications and length of stay, especially in colorectal and duodenal-pancreatic surgery [ 47 ]. In many cases, it is used following a strong recommendation despite having a low level of evidence.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of Immunonutrition on Cancer Patients Undergoing Surgery: A Scoping Review

et al. 2023

View full text Add to dashboard Cite

Introduction: There is a large body of evidence about immunonutrition formulas; however, there are still doubts about their usefulness in routine clinical practice as compared with standard formulas. In the age of personalized medicine, new studies appear every year regarding several types of patients; therefore, an updated point of view on these formulas is necessary. Methods: The Embase database was searched from 2016 to 14 March 2022. Our criteria were articles published in English and Spanish. The evidence quality was evaluated using GRADEpro, and the review was developed according to the PRISMA statement. Results: In this review, a total of 65 unique records were retrieved; however, 36 articles did not meet the inclusion criteria and were thus excluded. In total, 29 articles were included in the final analysis. In the last few years, many meta-analyses have attempted to identify additional existing studies of surgical patients with certain pathologies, mainly oncological patients. Immunonutrition prior to oncological surgery was shown to cause a decrease in inflammatory markers in most of the studies, and the main clinical events that changed were the infectious complications after surgery. The length of stay and mortality data are controversial due to the specific risk factors associated with these events. Conclusions: The use of immunonutrition in patients who have undergone oncological surgery decreases the levels of inflammatory markers and infectious postoperative complications in almost all localizations. However, more studies are needed to assess the use of immunonutrition based on Enhanced Recovery After Surgery (ERAS) protocols.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Effects of Immunonutrition on Cancer Patients Undergoing Surgery: A Scoping Review

et al. 2023

View full text Add to dashboard Cite

show abstract

Effect of Radical Laparoscopic Surgery and Conventional Open Surgery on Surgical Outcomes, Complications, and Prognosis in Elderly Patients with Bladder Cancer

Chen

Pan

et al. 2022

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

Background. Bladder cancer is a common malignant tumor of the urinary system in the clinic. It has multiple lesions, easy recurrence, easy metastasis, poor prognosis, and high mortality. Objective. The aim of this study is to investigate the impact of laparoscopic radical cystectomy (LRC) and open radical cystectomy (ORC) on the surgical outcome, complications, and prognosis of elderly patients with bladder cancer. Materials and Methods. One hundred elderly bladder cancer patients who underwent surgery in our hospital from June 2019 to June 2021 were selected for the retrospective study and were divided into 50 cases each in the ORC group and the LRC group according to the different surgical methods. The ORC group was treated with ORC, and the LRC group implemented LRC treatment. The differences in surgery, immune function, recent clinical outcomes, and complications between the two groups were observed and compared. Results. The mean operative time, mean intraoperative bleeding, intraoperative and postoperative transfusion rate, and transfusion volume of patients in the LRC group were statistically significant when compared to the ORC group. The differences in the meantime to resume eating, time to get out of bed, mean number of days in hospital after surgery, and the amount of postoperative numbing analgesics used by patients in the LRC group after surgery were statistically significant compared to the ORC group ( P < 0.05 ). There was no statistically significant difference in the comparison of immune function between the two groups before surgery ( P > 0.05 ), while the comparison of CD8+ and B cells 1 week after surgery of the LRC group was significantly better than that of the ORC group ( P < 0.05 ), and the operation time of the LRC group was longer than that of the ORC group ( P < 0.05 ). Statistical analysis of postoperative complications showed that the overall incidence of postoperative complications in the LRC group was significantly lower than that in the ORC group (16.67% vs. 46.67%) ( P < 0.05 ). Conclusion. LRC has less surgical trauma and intraoperative bleeding, faster postoperative recovery, and fewer postoperative complications, providing some reference for clinical surgery for elderly bladder cancer patients.

show abstract

Mortality Trends Related to Bladder Cancer in Spain, 1999–2018

Sanz

Martínez-Cayuelas

Gil-Guillén

et al. 2022

JCM

View full text Add to dashboard Cite

Bladder cancer (BC) is an important cause of premature mortality (PM, <75 years). Spain has one of the highest BC mortality rates in Europe. The objective of this study was to analyse BC mortality trends between 1999 and 2018 in Spain. The study was based on data from the National Institute of Statistics (Instituto Nacional de Estadística—INE). Age-adjusted mortality rates (AAMRs) were calculated by sex and age group. A trend analysis was performed using Joinpoint regression models and years of potential life lost (YPLL). Mortality in men resulting from BC decreased in all age groups studied. This was not observed in women, for whom mortality only decreased in the ≥75 age group. Deaths due to BC occurred prematurely in 38.6% of men and in 23.8% of women, which indicated a greater impact on YPLL in men compared to women. Over the last 20 years, there has been a significant decrease in BC mortality rate, except in women under 75 years of age. Despite this temporal trend of decreasing mortality, BC continues to have a significant impact on YPLL, mainly in men. Given this context, it is important to direct more resources towards prevention and early diagnosis strategies to correct this situation.

show abstract

Progressive perioperative benefits of laparoscopy in combination with an ERAS (Enhanced Recovery After Surgery) protocol in radical cystectomy with ileal conduit

Cited by 3 publications

References 26 publications

Effects of Immunonutrition on Cancer Patients Undergoing Surgery: A Scoping Review

Effects of Immunonutrition on Cancer Patients Undergoing Surgery: A Scoping Review

Effect of Radical Laparoscopic Surgery and Conventional Open Surgery on Surgical Outcomes, Complications, and Prognosis in Elderly Patients with Bladder Cancer

Mortality Trends Related to Bladder Cancer in Spain, 1999–2018

Contact Info

Product

Resources

About