Progressive multifocal leukoencephalopathy presenting with confusion and behavioral disturbances in an HIV-negative patient

Progressive multifocal leukoencephalopathy cannot be due to liver cirrhosis alone

“…It was concluded that PML can have multiple clinical manifestations and affect patients with mild or transient immunosuppression. 1 The study is excellent but has concerning limitations that should be discussed.…”

“…We read with interest the article by Almeida et al 1 on a 57 year-old male with progressive, multifocal leukoencephalopathy (PML) attributed to liver cirrhosis. It was concluded that PML can have multiple clinical manifestations and affect patients with mild or transient immunosuppression.…”